NCT06322082

Brief Summary

120 Patients with urinary incontinence following radical prostatectomy would be randomly assigned to either 4 groups all receive conventional pelvic floor muscle exercises plus group A receive Pilates exercises and Low Intensity Extracorporeal Shock Wave Therapy, group B receive Low Intensity Extracorporeal Shock Wave Therapy, group C receive Pilates exercises and group D receive conventional pelvic floor muscle exercises. Assessment at baseline, immediately after the intervention, to evaluate the degree of urinary incontinence and quality of life after three months from treatment.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 14, 2024

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 20, 2024

Completed
Same day until next milestone

Study Start

First participant enrolled

March 20, 2024

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 30, 2024

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 15, 2024

Completed
Last Updated

March 28, 2024

Status Verified

March 1, 2024

Enrollment Period

7 months

First QC Date

February 14, 2024

Last Update Submit

March 27, 2024

Conditions

Outcome Measures

Primary Outcomes (2)

  • Cystometry

    Ithe dynamic measurement of detrusor pressure during the continuous filling of the bladder.

    before treatment and after 3 months

  • Severity index scale

    measure frequency and amount of urine loss ,calculated by this equation: Severity index of incontinence = (Points for frequency of urine loss) × (Points for amount of urine loss) calculated by this equation: Severity index of incontinence = (Points for frequency of urine loss) × (Points for amount of urine loss) measure frequency and amount of urine loss to calculate severity of incontinence, o Frequency of urine loss grades: Never = 0 less than once a month= 1 once to several times a month = 2 once to several times a week = 3 Every day and/or night = 4 * o Amount of urine loss grades: No drop (completely dry) = 0 A few drops = 1 A little = 2 More = 3

    before treatment and after 3 months

Secondary Outcomes (1)

  • body mass index

    before treatment and after 3 months

Study Arms (4)

Pilates and Shock Wave group

EXPERIMENTAL

30 patients will receive Pilates exercises combined with Low Intensity Extracorporeal Shock Wave Therapy and conventional pelvic floor muscle exercises

Device: The DUOLITH SD1-TOP focused shock wave system (STORZ MEDICAL AG)

Shock Wave group

EXPERIMENTAL

30 patients will receive Low Intensity Extracorporeal Shock Wave Therapy and conventional pelvic floor muscle exercises.

Device: The DUOLITH SD1-TOP focused shock wave system (STORZ MEDICAL AG)

Pilates group

EXPERIMENTAL

30 patients will receive Pilates exercises and conventional pelvic floor muscle exercises

Device: The DUOLITH SD1-TOP focused shock wave system (STORZ MEDICAL AG)

control group

EXPERIMENTAL

30 patients will receive conventional pelvic floor muscle exercises

Device: The DUOLITH SD1-TOP focused shock wave system (STORZ MEDICAL AG)

Interventions

The LiESWT was applied to Pilates and Shock Wave group and Shock Wave group with 0.25 mJ/mm2 of intensity, 3000 pulses of shock, and 3 pulses/s of frequency, applicator was placed on the suprapubic skin area one session in the week for twelve weeks, totaling 12 sessions. Pilates exercises were performed to Pilates and Shock Wave group and Pilates group. The sessions of Pilates were applied twice a week for twelve weeks, totaling 24 sessions. The 50 min Pilates sessions were divided into three phases: warm-up, strengthening, and stretching. They also received written orientations to perform three exercises and two of the Pilates session at home every day - Conventional pelvic floor exercises performed for all groups include Kegel exercise, squats, bridging, and squeeze and release exercises. These exercises were performed 3 times per day, lasting for 12 consecutive weeks

Also known as: Pilates exercises, conventional pelvic floor muscle exercises
Pilates and Shock Wave groupPilates groupShock Wave groupcontrol group

Eligibility Criteria

Age40 Years - 75 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All patients diagnosed as urinary incontinence.
  • Age between 40 -75 male patients or older.
  • All patients received the same medical treatment

You may not qualify if:

  • adjuvant or neoadjuvant chemo-radiation therapy.
  • severe postoperative complications.
  • history of pelvic surgery, and diseases that could affect voiding function and limitations for the exercise program such as for patients with serious cardiovascular events or spinal or articular disease.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

faculty of physical therapy , Cairo university

Giza, Egypt

Location

MeSH Terms

Conditions

Urinary Incontinence, Stress

Interventions

Exercise Movement Techniques

Condition Hierarchy (Ancestors)

Urinary IncontinenceUrination DisordersUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesLower Urinary Tract SymptomsUrological ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Physical Therapy ModalitiesTherapeutics

Study Officials

  • Marwa Eid

    Professor at Faculty of physical therapy, Cairo University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
assist professor

Study Record Dates

First Submitted

February 14, 2024

First Posted

March 20, 2024

Study Start

March 20, 2024

Primary Completion

October 30, 2024

Study Completion

December 15, 2024

Last Updated

March 28, 2024

Record last verified: 2024-03

Data Sharing

IPD Sharing
Will share

120 male Patients with urinary incontinence would be randomly assigned to 4 groups all receive conventional pelvic floor exercises(CPFE) plus group A receive Pilates exercises and Low Intensity Extracorporeal Shock Wave Therapy (LiECSWT), group B receive (LiECSWT), group C receive Pilates exercises and group D receive conventional pelvic floor muscle exercises only. (LiECSWT) was applied with 0.25 mJ/mm2 of intensity, 3000 pulses of shock, and 3 pulses/s of frequency, one session in the week for twelve weeks. Pilates exercises twice a week for twelve weeks, totaling 24 sessions and (CPFE) were performed 3 times per day, lasting for 12 consecutive weeks. Assessment at baseline, immediately after the intervention, by Urodynamic investigation system, Severity index scale, Cytometry and The quality of life questionnaire IQOL.

Shared Documents
STUDY PROTOCOL, ICF
Time Frame
3 months
Access Criteria
Inclusion criteria : * All patients diagnosed as urinary incontinence. * Age between 40 -75 male patients or older. • All patients received the same medical treatment Exclusion criteria: * adjuvant or neoadjuvant chemo-radiation therapy. * severe postoperative complications. * history of pelvic surgery, and serious cardiovascular events or spinal or articular disease.

Locations