NCT06321952

Brief Summary

A randomized controlled trial was conducted with 72 participants who had moderate knee osteoarthritis (Kellgren and Lawrence grade 2-3). The patients were randomly assigned to either the robotic-assisted or gyroscopic-assisted group. Baseline characteristics, including age, body mass index, length of stay, and estimated blood loss, were recorded. The primary outcome measure was the accuracy of the hip knee angle, measured by scannogram film preoperatively and postoperatively at 3 months. Secondary outcomes included functional outcomes (KOOS, Oxford knee score, EQ-5D-5L, range of motion) assessed preoperatively and postoperatively at 3 months, as well as at 6 months postoperatively.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
64

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2021

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 17, 2021

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 22, 2023

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2024

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

February 12, 2024

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 20, 2024

Completed
Last Updated

March 20, 2024

Status Verified

March 1, 2024

Enrollment Period

2.1 years

First QC Date

February 12, 2024

Last Update Submit

March 13, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • accuracy of Robotic Assisted Surgery and Gyroscopic Based Instrument

    accuracy of the hip knee angle, measured by scannogram film preoperatively and postoperatively at 3 months

    preoperative and postoperative 3months

Secondary Outcomes (4)

  • Functional Outcome of Robotic Assisted Surgery and Gyroscopic Based Instrument

    preoperative and postoperative 3months and 6months

  • Functional Outcome of Robotic Assisted Surgery and Gyroscopic Based Instrument

    preoperative and postoperative 3months and 6months

  • Functional Outcome of Robotic Assisted Surgery and Gyroscopic Based Instrument

    preoperative and postoperative 3months and 6months

  • Functional Outcome of Robotic Assisted Surgery and Gyroscopic Based Instrument

    preoperative and postoperative 3months and 6months

Study Arms (2)

ROSA robotic assist TKA

ACTIVE COMPARATOR

ROSA robotic assist TKA

Device: ROSA robotic assist TKA

iassist TKA

ACTIVE COMPARATOR

iassist TKA

Procedure: iassist TKA

Interventions

total knee replacement with ROSA robotic assist

Also known as: iassist TKA
ROSA robotic assist TKA
iassist TKAPROCEDURE

total knee replacement with iassist

iassist TKA

Eligibility Criteria

Age55 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • primary osteoarthritis knee with indicated for total knee replacement
  • age equal or more than 55 years old

You may not qualify if:

  • revision surgery
  • deformity greater than 15º
  • Intra/Post operative complication

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Siriraj Hospital

Bangkok, 10700, Thailand

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Randomized Controlled Trial
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 12, 2024

First Posted

March 20, 2024

Study Start

September 17, 2021

Primary Completion

October 22, 2023

Study Completion

February 1, 2024

Last Updated

March 20, 2024

Record last verified: 2024-03

Locations