The Effect of Different Patient Positions on Endotracheal Tube Cuff Pressure

NCT06321835 | Completed

• 1 other identifier: 16-10/13
• Study Type: observational
• Target: 200
• Locations: 0 countries
• Sites: N/A

Brief Summary

Background: The placement of a cuffed endotracheal tube for the administration of general anesthesia is a routine procedure. In the part of the intubation tube located in the trachea, there is a balloon (cuff) to prevent gase leakage, aspiration of secretions and gastric contents into the lungs. Inadequate inflation of cuff may lead to inadequate ventilation, aspiration and associated complications, while excessive inflation may cause complications in ranging from postoperative pharyngeal complaints to tracheal rupture due to increased cuff pressure. This study aimed to determine the effect of different patient positions on the endotracheal cuff pressure in patients undergoing urological procedures. Methods: This is a prospective study conducted on 200 patients undergoing urological procedures in supine, prone, lateral flank and litotomy positions. After intubation (T0), the cuff pressure was checked with a cuff manometer and adjusted at 25 cmH2O as the baseline and continuously monitored. The cuff pressure was checked again before (T1) and after achieving the final position (T2) and then at 5 (T3), 10 (T4), 15 (T5), 30, 45, 60, 90, 120, 150, 180 minutes after the position, at the end of the procedure (T6) and before extubation (T7). At postoperative 2nd and 12th hours, the patients were interviewed for sore throat, hoarseness and cough.

Conditions

Endotracheal Tube Cuff Pressure; Patient Positions

Keywords

endotracheal tube; cuff pressure; patient position; prone; lateral flank; litotomy; sore throat

Outcome Measures

Primary Outcomes (1)

• The Effect of Different Patient Positions on Endotracheal Tube Cuff Pressure in Patients Undergoing Urological Procedures: A Prospective Study

  Primary outcome of this study is endotracheal cuff pressure can be changed in patients undergoing urological procedures in different patient positions.

  1 year

Secondary Outcomes (1)

• The Effect of Different Patient Positions on Endotracheal Tube Cuff Pressure in Patients

  1 year

Study Arms (4)

Supine Group

The patients were divided into four groups according to the operation position as supine, lateral flank, prone and lithotomy.

Procedure: Endotracheal tube cuff pressure measurement

Prone Group

The patients were divided into four groups according to the operation position as supine, lateral flank, prone and lithotomy.

Procedure: Endotracheal tube cuff pressure measurement

Lithotomy Group

The patients were divided into four groups according to the operation position as supine, lateral flank, prone and lithotomy.

Procedure: Endotracheal tube cuff pressure measurement

Lateral flank group

The patients were divided into four groups according to the operation position as supine, lateral flank, prone and lithotomy.

Procedure: Endotracheal tube cuff pressure measurement

Interventions

Endotracheal tube cuff pressure measurement PROCEDURE

This is a prospective study conducted on 200 patients undergoing urological procedures in supine, prone, lateral flank and litotomy positions. After intubation (T0), the cuff pressure was checked with a cuff manometer and adjusted at 25 cmH2O as the baseline and continuously monitored. The cuff pressure was checked again before (T1) and after achieving the final position (T2) and then at 5 (T3), 10 (T4), 15 (T5), 30, 45, 60, 90, 120, 150, 180 minutes after the position, at the end of the procedure (T6) and before extubation (T7). At postoperative 2nd and 12th hours, the patients were interviewed for sore throat, hoarseness and cough.

Lateral flank group; Lithotomy Group; Prone Group; Supine Group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

200 patients aged 18-75 years, ASA physical status I-II, who were planned for elective urological surgery in one of the supine, prone, lateral flank or lithotomy position were studied. The patients were divided into four groups according to the operation position as supine, lateral flank, prone and lithotomy

You may qualify if:

• patients aged 18-75 years
• ASA physical status I-II
• Who were planned for elective urological surgery in one of the supine, prone, lateral flank or lithotomy position were studied

You may not qualify if:

• emergency operation
• a history of chronic lung disease
• upper and/or lower respiratory tract infection within 2 weeks before surgery
• morbid obesity
• pregnancy
• laparoscopic surgery
• single lung ventilation
• difficut airway
• hemodynamic instability and/or respiratory complications in the intraoperative period
• history of mental illness or communication problems

Sponsors & Collaborators

• Ege University: lead

MeSH Terms

Conditions

Pharyngitis

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Pharyngeal Diseases; Stomatognathic Diseases; Respiratory Tract Diseases; Otorhinolaryngologic Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medical Doctor

Study Record Dates

• First Submitted: March 5, 2024
• First Posted: March 20, 2024
• Study Start: December 9, 2016
• Primary Completion: January 15, 2018
• Study Completion: June 15, 2018
• Last Updated: March 20, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will not share