Presentation of Protoscolexes and Acephalocysts in the Fibrous Capsule Area of the Liver With Echinococcosis

NCT06316154 | Recruiting DMC

• 1 other identifier: 12032024
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of the study is to determine the presence of germinal elements of echinococcosis in the liver parenchyma next to and in the thickness of the fibrous capsule of hydatid cysts.

Conditions

Echinococcosis, Hepatic

Outcome Measures

Primary Outcomes (1)

• Presence of viable germinal elements of echinococcosis

  Identification of viable germinal elements of echinococcosis according to morphological analysis

  1 day

Secondary Outcomes (1)

• Recurrence of liver echinococcosis

  1 year

Interventions

Echinococcectomy PROCEDURE

Echinococcectomy with subsequent pathomorphological analysis of liver parenchyma next to and in the thickness of the fibrous capsule

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with primary or recurrent liver echinococcosis

You may qualify if:

• Presence of primary or recurrent liver echinococcosis disease requiring surgical treatment
• Cyst diametr \>5 cm;
• Performing one of the surgical treatment of liver echinococcosis with intraoperative sampling of part of the fibrous capsule with or without adjacent liver tissue for research;

You may not qualify if:

• Liver echinococcosis with cysts less than 5 cm in diametr;
• Presence of severe concomitant disorders

Sponsors & Collaborators

• Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov: lead

Study Sites (1)

Republican specialized scientific and practical medical center of surgery named after academician V.Vakhidov

Tashkent, Uzbekistan, 100115, Uzbekistan

RECRUITING

MeSH Terms

Conditions

Echinococcosis, Hepatic

Condition Hierarchy (Ancestors)

Echinococcosis; Cestode Infections; Helminthiasis; Parasitic Diseases; Infections; Liver Diseases, Parasitic; Liver Diseases; Digestive System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: March 12, 2024
• First Posted: March 18, 2024
• Study Start: October 22, 2023
• Primary Completion (Estimated): December 22, 2026
• Study Completion (Estimated): December 25, 2026
• Last Updated: December 30, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

UZ (1)