Inspiratory Muscle Training in Burned Adults

NCT06315712 | Completed

• 1 other identifier: 004201
• Study Type: interventional
• Target: 52
• Locations: 1 country
• Sites: 1

Brief Summary

The study outlines burn injury impact, emphasizes need for long-term rehabilitation. Study assesses inspiratory muscle training efficacy in improving respiratory strength, lung function, and exercise capacity in adult burn patients.

Conditions

Burn Injuries

Outcome Measures

Primary Outcomes (10)

• maximal inspiratory pressure

  performed using an electronic respiratory pressure meter, measures inspiratory muscle strength

  At the beginning of intervention

• maximal inspiratory pressure

  performed using an electronic respiratory pressure meter, measures inspiratory muscle strength

  After 8 weeks of intervention

• maximal expiratory pressure

  performed using an electronic respiratory pressure meter, assesses expiratory muscle strength.

  At the beginning of intervention

• maximal expiratory pressure

  performed using an electronic respiratory pressure meter, assesses expiratory muscle strength.

  After 8 weeks of intervention

• Forced expiratory volume in 1 second

  performed using a spirometer

  At the beginning of intervention

• Forced expiratory volume in 1 second

  performed using a spirometer

  After 8 weeks of intervention

• forced vital capacity

  performed using a spirometer

  At the beginning of intervention

• forced vital capacity

  performed using a spirometer

  After 8 weeks of intervention

• Forced expiratory volume in 1 second/ forced vital capacity ratio

  performed using a spirometer

  At the beginning of intervention

• Forced expiratory volume in 1 second/ forced vital capacity ratio

  performed using a spirometer

  After 8 weeks of intervention

Secondary Outcomes (2)

• Functional exercise capacity

  At the beginning of intervention

• Functional exercise capacity

  After 8 weeks of intervention

Study Arms (2)

Respiratory muscle training group

EXPERIMENTAL

Received inspiratory muscle training plus pulmonary rehabilitation program. Powerbreathe device was used for the exercise of the inspiratory muscle strength. Strengthening the inspiratory muscles with the Powerbreathe is similar to weightlifting to strengthen other muscles in the body.

Other: inspiratory exercise; Other: Pulmonary rehabilitation

Pulmonary rehabilitation group

EXPERIMENTAL

Received pulmonary rehabilitation program for five sessions per week for 8 weeks. Four resistive exercises, aerobic exercise, and deep breathing exercises, aerobic conditioning exercises on the treadmill. All exercises were performed using variable resistance machines.

Other: Pulmonary rehabilitation

Interventions

inspiratory exercise OTHER

The training consisted of 6 sets of 30 breaths per day, divided into 2 sessions per day. A one-minute rest interval between each set. Training was prescribed 5 days a week for 8 weeks

Also known as: inspiratory muscle training

Respiratory muscle training group

Pulmonary rehabilitation OTHER

Four resistive exercises, aerobic exercise, and deep breathing exercises, five sessions per week for 8 weeks

Also known as: Resistance exercise

Pulmonary rehabilitation group; Respiratory muscle training group

Eligibility Criteria

• Age: 20 Years - 49 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Burn-injured adults aged 20-49.
• Admitted to the clinic after acute treatment.
• Recovering from burns affecting at least 20% total body surface area.
• Partial or full-thickness burns.

You may not qualify if:

• Smokers.
• had open or unhealed wounds.
• had any known neurological deficit.
• neuromuscular diseases.
• musculoskeletal deformities.
• pulmonary diseases.
• severe cardiac problems.
• inability to participate in regular exercise.

Sponsors & Collaborators

• Qassim University: lead
• Cairo University: collaborator

Study Sites (1)

Faculty of Physical Therapy, Cairo University

Giza, Dokki, 11432, Egypt

Location

Related Publications (3)

• Willis CE, Grisbrook TL, Elliott CM, Wood FM, Wallman KE, Reid SL. Pulmonary function, exercise capacity and physical activity participation in adults following burn. Burns. 2011 Dec;37(8):1326-33. doi: 10.1016/j.burns.2011.03.016. Epub 2011 May 6.

  PMID: 21530086 BACKGROUND

• Ozkal O, Topuz S, Karahan S, Erdem MM, Konan A, Yasti AC. Clinical predictors of pulmonary functions, respiratory/peripheral muscle strength and exercise capacity at discharge in adults with burn injury. Disabil Rehabil. 2021 Oct;43(20):2875-2881. doi: 10.1080/09638288.2020.1720320. Epub 2020 Jan 30.

  PMID: 31999499 BACKGROUND

• Gittings PM, Grisbrook TL, Edgar DW, Wood FM, Wand BM, O'Connell NE. Resistance training for rehabilitation after burn injury: A systematic literature review & meta-analysis. Burns. 2018 Jun;44(4):731-751. doi: 10.1016/j.burns.2017.08.009. Epub 2017 Oct 7.

  PMID: 29017743 RESULT

MeSH Terms

Conditions

Burns

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Wounds and Injuries

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• FatmaAlzahraa Kamel, PhD

  Cairo University

  PRINCIPAL INVESTIGATOR

• Maged Basha, PhD

  Qassim University

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor, College of Applied Medical Sciences, Qassim University

Study Record Dates

• First Submitted: March 12, 2024
• First Posted: March 18, 2024
• Study Start: January 15, 2021
• Primary Completion: June 16, 2022
• Study Completion: September 11, 2023
• Last Updated: March 18, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: 6 months after publication
• Access Criteria: relevance to the topic of the study and approval of all co-authors within 1 month of receiving the request.

Locations

EG (1)