NCT06312631

Brief Summary

On a functional level, performing the actions of daily life requires coordinated activity of the muscles of the upper limbs. The quality of motor recovery and/or technical assistance aimed at compensating for the movement deficit of the paretic upper limb (MSP) determines the possibilities of using the upper limb (MS) in activities of daily life. Interventions in the chronic phase of stroke aim to return home. The integration of the paretic upper limb into daily life activities is a major issue regarding the prognosis of recovery of use of the upper limb. Independence in daily life becomes an ultimate goal to take charge of. This study focuses on a new technical aid device, standard orthosis type, expanding the range of gripping gloves: the SaeboGlove in everyday environments. These MS orthoses help improve the use and function of the MSP in post-stroke adults as well as their independence and participation in society.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P75+ for not_applicable stroke

Timeline
19mo left

Started Mar 2024

Longer than P75 for not_applicable stroke

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress59%
Mar 2024Dec 2027

First Submitted

Initial submission to the registry

March 8, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 15, 2024

Completed
11 days until next milestone

Study Start

First participant enrolled

March 26, 2024

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2027

Last Updated

June 1, 2026

Status Verified

May 1, 2026

Enrollment Period

3.8 years

First QC Date

March 8, 2024

Last Update Submit

May 28, 2026

Conditions

Keywords

brain-injured adult

Outcome Measures

Primary Outcomes (1)

  • Evaluation of the effectiveness of the gripping glove

    The evaluation of the effectiveness of the gripping glove on the performance of the upper limb in daily life will be evaluated using the ULPA score and compared between the 2 conditions (with and without the glove) in the performance of a daily activity.

    6 months

Secondary Outcomes (8)

  • Evaluation of the performance of an activity in the real context of the patient

    6 months

  • Evaluation of factual spontaneous use of the upper limb in daily life

    6 months

  • Evaluation of the perceived performance of the use of the paretic upper limb

    6 months

  • Assessment of the quality of voluntary motor skills of the upper limb

    6 months

  • Assessment of gripping abilities

    6 months

  • +3 more secondary outcomes

Study Arms (8)

Task handover model #1

EXPERIMENTAL

At each visit, the patient will perform the tasks with the gripping glove (A) or without the gripping glove (B). The order of administration "with then without the glove (AB)" or "without then with the glove (BA)" is drawn at random for each patient. The 1st model follows the following diagram: Visit T1 = AB; Visit T2 = AB; Visit T3 = AB

Device: Putting on the gripping gloveOther: ULPA questionnaireOther: Motor Activity Log (MAL) QuestionnaireOther: Fugl-Meyer Assessment Upper Extremity (FMA-UE) questionnaireOther: Score Action Arm Research TestOther: EuroQol five-level (EQ-5D-5L) questionnaireOther: Quebec User Evaluation of Satisfaction with Assistive TechnologyOther: Psychosocial Impact of Assistive Devices Scale (PIADS)Other: Goal Attainment Scale (GAS)Other: installation and collection of accelerometers

Task handover model #2

EXPERIMENTAL

At each visit, the patient will perform the tasks with the gripping glove (A) or without the gripping glove (B). The order of administration "with then without the glove (AB)" or "without then with the glove (BA)" is drawn at random for each patient. The 2nd model follows the following diagram: Visit T1 = BA ; Visit T2 = AB ; Visit T3 = AB

Device: Putting on the gripping gloveOther: ULPA questionnaireOther: Motor Activity Log (MAL) QuestionnaireOther: Fugl-Meyer Assessment Upper Extremity (FMA-UE) questionnaireOther: Score Action Arm Research TestOther: EuroQol five-level (EQ-5D-5L) questionnaireOther: Quebec User Evaluation of Satisfaction with Assistive TechnologyOther: Psychosocial Impact of Assistive Devices Scale (PIADS)Other: Goal Attainment Scale (GAS)Other: installation and collection of accelerometers

Task handover model #3

EXPERIMENTAL

At each visit, the patient will perform the tasks with the gripping glove (A) or without the gripping glove (B). The order of administration "with then without the glove (AB)" or "without then with the glove (BA)" is drawn at random for each patient. The 3rd model follows the following diagram: Visit T1 = AB ; Visit T2 = BA ; Visit T3 = AB

Device: Putting on the gripping gloveOther: ULPA questionnaireOther: Motor Activity Log (MAL) QuestionnaireOther: Fugl-Meyer Assessment Upper Extremity (FMA-UE) questionnaireOther: Score Action Arm Research TestOther: EuroQol five-level (EQ-5D-5L) questionnaireOther: Quebec User Evaluation of Satisfaction with Assistive TechnologyOther: Psychosocial Impact of Assistive Devices Scale (PIADS)Other: Goal Attainment Scale (GAS)Other: installation and collection of accelerometers

Task handover model #4

EXPERIMENTAL

At each visit, the patient will perform the tasks with the gripping glove (A) or without the gripping glove (B). The order of administration "with then without the glove (AB)" or "without then with the glove (BA)" is drawn at random for each patient. The 4th model follows the following diagram: Visit T1 = AB ; Visit T2 = AB ; Visit T3 = BA

Device: Putting on the gripping gloveOther: ULPA questionnaireOther: Motor Activity Log (MAL) QuestionnaireOther: Fugl-Meyer Assessment Upper Extremity (FMA-UE) questionnaireOther: Score Action Arm Research TestOther: EuroQol five-level (EQ-5D-5L) questionnaireOther: Quebec User Evaluation of Satisfaction with Assistive TechnologyOther: Psychosocial Impact of Assistive Devices Scale (PIADS)Other: Goal Attainment Scale (GAS)Other: installation and collection of accelerometers

Task handover model #5

EXPERIMENTAL

At each visit, the patient will perform the tasks with the gripping glove (A) or without the gripping glove (B). The order of administration "with then without the glove (AB)" or "without then with the glove (BA)" is drawn at random for each patient. The 5th model follows the following diagram: Visit T1 = BA ; Visit T2 = BA ; Visit T3 = AB

Device: Putting on the gripping gloveOther: ULPA questionnaireOther: Motor Activity Log (MAL) QuestionnaireOther: Fugl-Meyer Assessment Upper Extremity (FMA-UE) questionnaireOther: Score Action Arm Research TestOther: EuroQol five-level (EQ-5D-5L) questionnaireOther: Quebec User Evaluation of Satisfaction with Assistive TechnologyOther: Psychosocial Impact of Assistive Devices Scale (PIADS)Other: Goal Attainment Scale (GAS)Other: installation and collection of accelerometers

Task handover model #6

EXPERIMENTAL

At each visit, the patient will perform the tasks with the gripping glove (A) or without the gripping glove (B). The order of administration "with then without the glove (AB)" or "without then with the glove (BA)" is drawn at random for each patient. The 6th model follows the following diagram: Visit T1 = BA ; Visit T2 = AB ; Visit T3 = BA

Device: Putting on the gripping gloveOther: ULPA questionnaireOther: Motor Activity Log (MAL) QuestionnaireOther: Fugl-Meyer Assessment Upper Extremity (FMA-UE) questionnaireOther: Score Action Arm Research TestOther: EuroQol five-level (EQ-5D-5L) questionnaireOther: Quebec User Evaluation of Satisfaction with Assistive TechnologyOther: Psychosocial Impact of Assistive Devices Scale (PIADS)Other: Goal Attainment Scale (GAS)Other: installation and collection of accelerometers

Task handover model #7

EXPERIMENTAL

At each visit, the patient will perform the tasks with the gripping glove (A) or without the gripping glove (B). The order of administration "with then without the glove (AB)" or "without then with the glove (BA)" is drawn at random for each patient. The 7th model follows the following diagram: Visit T1 = AB ; Visit T2 = BA ; Visit T3 = BA

Device: Putting on the gripping gloveOther: ULPA questionnaireOther: Motor Activity Log (MAL) QuestionnaireOther: Fugl-Meyer Assessment Upper Extremity (FMA-UE) questionnaireOther: Score Action Arm Research TestOther: EuroQol five-level (EQ-5D-5L) questionnaireOther: Quebec User Evaluation of Satisfaction with Assistive TechnologyOther: Psychosocial Impact of Assistive Devices Scale (PIADS)Other: Goal Attainment Scale (GAS)Other: installation and collection of accelerometers

Task handover model #8

EXPERIMENTAL

At each visit, the patient will perform the tasks with the gripping glove (A) or without the gripping glove (B). The order of administration "with then without the glove (AB)" or "without then with the glove (BA)" is drawn at random for each patient. The 8th model follows the following diagram: Visit T1 = BA ; Visit T2 = BA ; Visit T3 = BA

Device: Putting on the gripping gloveOther: ULPA questionnaireOther: Motor Activity Log (MAL) QuestionnaireOther: Fugl-Meyer Assessment Upper Extremity (FMA-UE) questionnaireOther: Score Action Arm Research TestOther: EuroQol five-level (EQ-5D-5L) questionnaireOther: Quebec User Evaluation of Satisfaction with Assistive TechnologyOther: Psychosocial Impact of Assistive Devices Scale (PIADS)Other: Goal Attainment Scale (GAS)Other: installation and collection of accelerometers

Interventions

taking measurements and putting the gripping glove on the patient

Task handover model #1Task handover model #2Task handover model #3Task handover model #4Task handover model #5Task handover model #6Task handover model #7Task handover model #8

The evaluation of the effectiveness of the gripping glove on the performance of the upper limb in daily life will be evaluated using the ULPA score. The investigator asks the patient to perform a task and the ULPA collects the total number of errors made by the patient (inability/omission, imprecision, repetition, time to complete the task)

Task handover model #1Task handover model #2Task handover model #3Task handover model #4Task handover model #5Task handover model #6Task handover model #7Task handover model #8

The MAL is a self-assessment of the integration of the upper limb into daily life. This measurement allows a quantified evaluation of the perceived performance of the use of the upper limb in the actions of daily life. The patient will answer 30 questions about daily life and for each item, rate the quantity from 0 to 5: 0 = never uses the hemiplegic arm and 5 = uses as much as before the accident

Task handover model #1Task handover model #2Task handover model #3Task handover model #4Task handover model #5Task handover model #6Task handover model #7Task handover model #8

This questionnaire assesses the motor selectivity of the upper limb. Several questions are asked about the movements that the patient can perform and to each question, the patient can answer either 0 (minimum) and 2 (maximum).

Task handover model #1Task handover model #2Task handover model #3Task handover model #4Task handover model #5Task handover model #6Task handover model #7Task handover model #8

This questionnaire evaluates 4 different actions: Grasping an object (6 different objects to grasp), holding an object (4 different objects), pinching an object (6 different objects) and the overall movements made by the patient (3 different overall movements). For each item, each object or each movement evaluated, the patient must rate the task on a scale of 0 to 3 (0=cannot perform any part of the test and 3=performs the test normally)

Task handover model #1Task handover model #2Task handover model #3Task handover model #4Task handover model #5Task handover model #6Task handover model #7Task handover model #8

This questionnaire assesses the patient's state of health. 5 items are proposed (mobility, autonomy, current activity, pain, anxiety) and for each the patient must check one of the 5 propositions (no problem, mild problems, moderate problems, severe problems, incapable). The patient must also rate their state of health on a scale of 0 to 100.

Task handover model #1Task handover model #2Task handover model #3Task handover model #4Task handover model #5Task handover model #6Task handover model #7Task handover model #8

This questionnaire assesses satisfaction with the technical aid (here the gripping glove) and the related services. The technique and related services will be evaluated by items provided to the patient and he will have to rate for each of them a score between 1 and 5 (1 = not satisfied at all and 5 = very satisfied)

Task handover model #1Task handover model #2Task handover model #3Task handover model #4Task handover model #5Task handover model #6Task handover model #7Task handover model #8

This questionnaire measures the effect of technical aids on the psychosocial level. 26 sentences or words are offered to the patient concerning his psychological state and the patient must evaluate them between -3 and 3 (-3 = decreased and +3: increased)

Task handover model #1Task handover model #2Task handover model #3Task handover model #4Task handover model #5Task handover model #6Task handover model #7Task handover model #8

Carrying out an activity in the patient's real context is assessed using the Goal Attainment Scale (GAS). The doctor gives the patient objectives to achieve and the patient must give the quotation for each objective between initial state (-2), expected result (0) and best possible result (2)

Task handover model #1Task handover model #2Task handover model #3Task handover model #4Task handover model #5Task handover model #6Task handover model #7Task handover model #8

The accelerometer quantitatively reports the spontaneous use of the upper limb in daily life. It counts the number of voluntary movements of the upper limbs. The amount of movement of the paretic upper limb will be expressed as a percentage of the movements of the non-paretic limb.

Task handover model #1Task handover model #2Task handover model #3Task handover model #4Task handover model #5Task handover model #6Task handover model #7Task handover model #8

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient suffering from a motor deficit of the upper limb resulting from an ischemic or hemorrhagic stroke, hemispheric or brainstem, confirmed by brain imaging ;
  • Patient who suffered a stroke more than three months ago;
  • Patient unable to actively extend long fingers (hand opening) to voluntarily grasp an empty glass (upper and lower diameter of 7 and 6 cm respectively, height of 12 to 15 cm, weight of 125g, identical to equipment used for ARAT), with a palmar grip (cylindrical grip), while the subject can hold the previously placed glass passively in the hand;
  • Patient capable of passively opening the hand sufficient to grasp the glass when the gripping glove is put on, with the possibility of actively closing the hand;
  • Patient with the ability to put on and remove the SaeboGlove® gripping glove with the help of a third person if necessary and/or available.
  • Patient with a smartphone, tablet and/or computer compatible with video taking and teleconsultation.
  • Person affiliated to or beneficiary of a social security system.

You may not qualify if:

  • Patient presenting retraction or stiffness of the fingers and wrist preventing complete extension of the long fingers and thumb, the wrist being at 15° extension;
  • Patient with moderate or severe muscular spasticity of the wrist flexors and the long and short flexors of the fingers and thumb (Modified Ashworth Scale ≥ 3);
  • Patient with limited active elbow extension, not allowing the ipsilateral knee to be reached with the hand, the subject being seated with the trunk vertical (approach limitation);
  • Patient with an active anterior shoulder elevation range of less than 15°;
  • Patient with other upper limb deficiencies likely to influence participation;
  • Patient and/or entourage who do not have access to teleconsultation, and/or can be reached remotely;
  • Patient with severe aphasia, Boston Diagnostic Aphasia Examination (BDAE) ≤ 3;
  • Presence of moderate or severe edema localized to the wrist and hand;
  • Patient allergic to Latex
  • History of upper limb surgery less than 6 months old.
  • Pregnant and/or breastfeeding women
  • Patient deprived of liberty (detained/incarcerated);
  • Patient under judicial protection
  • Impossibility of giving the person informed information and ensuring the subject's compliance due to impaired physical and/or psychological health

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Claire VILLEPINTE

Toulouse, France

RECRUITING

MeSH Terms

Conditions

Stroke

Interventions

Surveys and QuestionnairesSelf-Help Devices

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Data CollectionEpidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public HealthEquipment and Supplies

Study Officials

  • Claire VILLEPINTE

    University Hospital, Toulouse

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 8, 2024

First Posted

March 15, 2024

Study Start

March 26, 2024

Primary Completion (Estimated)

December 31, 2027

Study Completion (Estimated)

December 31, 2027

Last Updated

June 1, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations