NCT06310460

Brief Summary

To evaluate the effectiveness and sefety of papillectomy to enable bile duct access during endoscopic retrograde cholangiography in patients with difficult biliary cannulation.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Apr 2024

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 7, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 15, 2024

Completed
17 days until next milestone

Study Start

First participant enrolled

April 1, 2024

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2024

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2025

Completed
Last Updated

March 15, 2024

Status Verified

March 1, 2024

Enrollment Period

9 months

First QC Date

March 7, 2024

Last Update Submit

March 7, 2024

Conditions

Outcome Measures

Primary Outcomes (2)

  • Rate of treatment success

    Rate of successful cannulation of the bile duct after PreCut-papillectomy

    During endoscopy

  • Adverse event rate

    Rate of adverse events, as classifed by ASGE classification

    Up to 30 days

Interventions

PapillectomyPROCEDURE

Papillectomy prior to bile duct cannulation during ERCP

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients undergoing ERCP with intented bile duct cannulation

You may qualify if:

  • Difficult cannulation of bile duct

You may not qualify if:

  • post-surgical upper GI anatomy
  • previous endoscopic retrograde cholangiopancreaticography or percutaneous transhepatic cholangiography
  • papilla within a diverticulum
  • coagulation disorder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 7, 2024

First Posted

March 15, 2024

Study Start

April 1, 2024

Primary Completion

December 31, 2024

Study Completion

February 28, 2025

Last Updated

March 15, 2024

Record last verified: 2024-03

Data Sharing

IPD Sharing
Will not share