NCT06309602

Brief Summary

Hypothesis: Use of a Free Water Protocol (FWP) will improve patient satisfaction scores (Dysphagia Handicap Index), will not increase the risk of aspiration pneumonia/pneumonitis, and will result in improved oral hygiene (as assessed by the Oral Assessment Guide). Aim: To demonstrate that improvement in patient satisfaction and quality of life scores outweighs the potential risks of aspiration of plain water in an acute care setting; to qualitatively assess the implementation of a Free Water Protocol from the viewpoints of the patient and family/caregivers; to quantify changes in oral hygiene practices for individuals on the Free Water Protocol.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
136

participants targeted

Target at P50-P75 for not_applicable

Timeline
20mo left

Started Oct 2024

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress48%
Oct 2024Jan 2028

First Submitted

Initial submission to the registry

November 2, 2023

Completed
4 months until next milestone

First Posted

Study publicly available on registry

March 13, 2024

Completed
7 months until next milestone

Study Start

First participant enrolled

October 22, 2024

Completed
3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2028

Last Updated

June 5, 2025

Status Verified

May 1, 2025

Enrollment Period

3.2 years

First QC Date

November 2, 2023

Last Update Submit

May 31, 2025

Conditions

Keywords

stroketrauma

Outcome Measures

Primary Outcomes (3)

  • Dysphagia Handicap Index

    Quality of life survey

    Through study completion, an average of 5 days

  • Oral Assessment Guide

    8-point visual assessment of oral hygiene

    Through study completion, an average of 5 days

  • Qualitative data

    Open-ended question to provide a narrative of patient impressions and satisfaction regarding eating and drinking

    Through study completion, an average of 5 days

Secondary Outcomes (2)

  • Adverse events: Aspiration pneumonia/pneumonitis

    Through study completion, an average of 5 days

  • Liquid intake

    Through study completion, an average of 5 days

Study Arms (2)

Control / Standard Care

OTHER

Standard care provided for patients with orders for thickened liquids.

Other: Control / Standard Care

Free Water Protocol

EXPERIMENTAL

Standard care provided for patients with orders for thickened liquids. Additionally, participant will be allowed to have plain, un-thickened water after the following have taken place: 1) Wait 30 minutes after meal or medication administration; 2) Complete oral care according to instructions posted at bedside.

Other: Free Water Protocol

Interventions

Intake of plain, un-thickened water is allowed even when a patient has orders for thickened liquids. Risks of pulmonary complications are decreased with use of a strict oral care regimen and timed intake of water related to meals. Patient satisfaction and comfort is increased with ingestion of plain water.

Free Water Protocol

Standard care will be given to patients with orders for thickened liquids. This will include oral care twice a day and implementation of swallowing strategies and precautions as prescribed by the treating speech-language pathologist. Only fluids thickened to the recommended viscosity will be available to the patient.

Control / Standard Care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Stroke diagnosis or trauma patients being cared for by Trauma \& Acute Care Surgery (TACS) providers
  • Current orders for restricted or thickened liquids
  • Ability to control their own airway (i.e. airway adjuncts not needed)

You may not qualify if:

  • Individuals who are medically fragile, as determined by treating physician, to include diagnosis of sepsis, need for vasopressors, or high oxygenation needs (requiring high-flow nasal cannula, Airvo, or oximask)
  • Individuals who refuse oral care, have any decayed teeth or dental disease, or have a documented active oral infection
  • Individuals with an advanced progressive neurological condition, active head/neck cancer, or those who are immunosuppressed
  • Individuals who are on bed-rest orders
  • Individuals who are lethargic or sedated
  • Individuals with suspected pre-hospital aspiration event and/or aspiration pneumonitis
  • Individuals with a fever of unknown origin
  • Individuals with a history of recurrent aspiration pneumonia/pneumonitis
  • Individuals whose primary language is one that the questionnaires are not available in a validated format

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Medical Center of the Rockies

Loveland, Colorado, 80538, United States

NOT YET RECRUITING

Medical Center of the Rockies

Loveland, Colorado, 80538, United States

RECRUITING

MeSH Terms

Conditions

Deglutition DisordersStrokeWounds and Injuries

Interventions

Standard of Care

Condition Hierarchy (Ancestors)

Esophageal DiseasesGastrointestinal DiseasesDigestive System DiseasesPharyngeal DiseasesOtorhinolaryngologic DiseasesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Quality Indicators, Health CareQuality of Health CareHealth Services AdministrationHealth Care Quality, Access, and Evaluation

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

November 2, 2023

First Posted

March 13, 2024

Study Start

October 22, 2024

Primary Completion (Estimated)

January 1, 2028

Study Completion (Estimated)

January 1, 2028

Last Updated

June 5, 2025

Record last verified: 2025-05

Locations