Application of the Recommendations of the SPLIF (French Society of Infectious Pathology) in a Geriatric Population on the Duration of Treatment for Bacterial Pneumonia

NCT06307730 | Completed

• 1 other identifier: CHSD_0033_GERIATRIE
• Study Type: observational
• Target: 35
• Locations: 1 country
• Sites: 1

Brief Summary

Pneumopathy is the leading cause of death from infectious disease in the elderly. Prior to 2021, the recommended duration of antibiotic therapy for pneumonia, in adults, was 7 days. Two theses have shown that these recommendations were poorly applied in geriatric services. Indeed, the duration of treatment exceeded 7 days, and less than 30% of antibiotic antibiotic treatments were re-evaluated at 72 hours. In 2021, the SPLIF ( published new recommendations reducing this duration to 5 days in the event of clinical improvement observed on the 3rd day of treatment. These new recommendations are based on studies, in which the average age of participants was 65 years. However, the average age of patients in geriatric short-stay departments is 84.7 years. In addition, the geriatric population is characterized by immunosenescence, pulmonary vulnerability and undernutrition, raising questions about the validity of these recommendations in the geriatric population. The investigators offer a monocentric, retrospective, observational study of the geriatric hospital Casanova to assess the application of SPLIF recommendations in the geriatric population.

Conditions

Pneumonia, Bacterial; Pneumopathy

Keywords

pneumopathy; Bacterial; nosocomial

Outcome Measures

Primary Outcomes (7)

• Sex

  Day 1

• Age

  Day 1

• Weight

  Day 1

• Phone Number

  Day 1

• Origins

  Coming from Home, An institution...

  Day 1

• Autonomy in daily life's score before hospitalisation

  score between 0 (autonomous) and 6 (dependent)

  Day 1

• Charlson's morbidity score

  Day 1

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients hospitalized in the geriatric short-stay unit at the Casanova's hospital in Seine-saint-Denis for pneumopathy, between January 2, 2023 and April 30, 2023.

You may qualify if:

• All patient treated for bacterial/community/nosocomial pneumonia who stayed in the geriatric short-stay at Casanova's Hospital between January 2, 2023 and April 30, 2023

You may not qualify if:

• HIV Positif
• Immunosupressed patient
• Complicated pneumonia (abcess, pleuropneumonia)

Sponsors & Collaborators

• Centre Hospitalier de Saint-Denis: lead

Study Sites (1)

Centre Hopitalier de Saint-Denis

Saint-Denis, Seine Saint Denis, 93200, France

Location

MeSH Terms

Conditions

Pneumonia, Bacterial; Lung Diseases

Condition Hierarchy (Ancestors)

Bacterial Infections; Bacterial Infections and Mycoses; Infections; Pneumonia; Respiratory Tract Infections; Respiratory Tract Diseases

Study Officials

• Louise BORIES

  Hôpital Delafontaine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 6, 2024
• First Posted: March 13, 2024
• Study Start: January 2, 2023
• Primary Completion: April 30, 2023
• Study Completion: April 30, 2023
• Last Updated: March 13, 2024

Record last verified: 2024-03

Locations

FR (1)