Assessment of Anti-aging Efficacy of Marine Collagen Peptides

NCT06306105 | Completed

• 1 other identifier: 23-118-B
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human

Conditions

Skin Condition; Hair Fragility; Nails, Ingrown

Keywords

fish collagen

Outcome Measures

Primary Outcomes (13)

• The change of skin hydation

  Corneometer® CM825 (CK, Germany) was utilized to measure skin surface hydation. Units: arbitrary Corneometer® units 0-120.

  Change from Baseline skin skin hydation at 12 weeks

• The change of skin wrinkles

  VISIA Complexion Analysis was utilized to measure skin wrinkles. Units: the amount of detectable wrinkles

  Change from Baseline skin wrinkles at 12 weeks

• The change of skin elasticity

  Cutometer® MPA580 was utilized to measure skin elasticity. Units: visco-elasticity in %.

  Change from Baseline skin elasticity at 12 weeks

• The change of skin collagen density

  DermaLab® Series SkinLab Combo was utilized to measure skin collagen density. Units: arbitrary units

  Change from Baseline skin collagen density at 12 weeks

• The change of hair diameters

  Mitutoyo C/N293-100 was utilized to measure hair diameters. Units: millimeter

  Change from Baseline hair diameters at 12 weeks

• The change of hair loss amount

  Collect and measure the weight of loss hair. Units: gram

  Change from Baseline hair loss amount at 12 weeks

• The change of hair roots diameters

  Mitutoyo C/N293-100 was utilized to measure hair roots diameters. Units: millimeter

  Change from Baseline hair roots diameters at 12 weeks

• The change of hair density

  Soft Plus was utilized to picture and observe hair density.

  Change from Baseline hair density at 12 weeks

• The change of hair follicle strength

  Pull up the hair of the frontal bone, temporal bone and occipital bone (approximately 60 hairs/area) to assess the number of hair loss in each area. Units: the number of loss hair

  Change from Baseline hair follicle strength at 12 weeks

• The change of thumbs nail color

  Chroma Meter MM500 was utilized to measure thumbs nail color. Units: L\* index

  Change from Baseline thumbs nail color at 12 weeks

• The change of nails appearence

  Picture taken was utilized to record and observe nails appearence.

  Change from Baseline nails appearence at 12 weeks

• The change of nails growth

  Marking the position of middle fingers lunula was utilized to record and observe nails growth. Units: milimeter

  Change from Baseline marking position at 12 weeks

• The degree of nails fragility

  Iron ruler was utilized to evaluate nails fragility. Picture taken was utilized to record and observe the change of nails fragility.

  Change from Baseline nails fragility at 12 weeks

Secondary Outcomes (1)

• The change of self-assessment skin, hair, and nails condition

  Change from Baseline skin, hair, and nails condition at 12 weeks

Study Arms (2)

placebo drink

PLACEBO COMPARATOR

Dietary Supplement: placebo drink

Marine Collagen Peptides drinks

EXPERIMENTAL

Dietary Supplement: Marine Collagen Peptides

Interventions

Marine Collagen Peptides DIETARY_SUPPLEMENT

consume 1 bottle per day

Also known as: Coral club Promarine Collagen Tripeptides

Marine Collagen Peptides drinks

placebo drink DIETARY_SUPPLEMENT

consume 1 bottle per day

placebo drink

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy adults aged above 18 years old

You may not qualify if:

• Subjects who are not volunteers
• Subjects who have been diagnosed with dermatitis, cirrhosis, and chronic kidney failure
• Subjects who have known cosmetic, drug or food allergies.
• Patients are taking medicine for chronic diseases
• Subjects receiving treatments for scalp, hair transplant, and other scalp medical care in past 12 weeks.
• Subjects getting a manicure and perm in past 12 weeks.
• Female who is pregnant or nursing or planning to become pregnant during the course of the study.
• Subjects receiving facial laser therapy, chemical peeling or UV overexposure (\> 3 hr/week) in the past 12 weeks.
• Students who are currently taking courses taught by the principal investigator of this trial.
• Subjects are not willing to reveal the results of pictures after taking the product
• Vegetarian.

Sponsors & Collaborators

• TCI Co., Ltd.: lead

Study Sites (1)

Chia Nan University of Pharmacy & Science

Pingtung City, 928, Taiwan

Location

MeSH Terms

Conditions

Skin Diseases; Nails, Ingrown

Condition Hierarchy (Ancestors)

Skin and Connective Tissue Diseases; Nail Diseases

Study Officials

• Chia-Hua Liang, Ph.D.

  Chia Nan University of Pharmacy ＆ Science

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 5, 2024
• First Posted: March 12, 2024
• Study Start: March 4, 2024
• Primary Completion: June 30, 2024
• Study Completion: August 31, 2024
• Last Updated: September 19, 2024

Record last verified: 2024-09

Locations

TW (1)