SiFi vs FNB Local Anesthesia for Hip Fracture Surgeries

NCT06296758 | Terminated

• 1 other identifier: SiFi_HIP FRACTURE
• Study Type: interventional
• Target: 17
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to compare two commonly used local/regional anesthesia techniques in adults patients undergoing hip fracture surgery. The main question\[s\] it aims to answer are: • the impact of both interventions on patient level of pain. • impact on postoperative analgesics administered Participants will be randomly assigned to one of two local/regional anesthesia techniques, either femoral nerve block (FNB) or suprainguinal fascia iliaca block (SiFi). Both techniques are the usual practice at the hospital, and we are NOT aiming to experiment on new anesthesia technique in this study.

Conditions

Hip Fractures; Surgery; Anesthesia, Local

Outcome Measures

Primary Outcomes (2)

• Postoperative pain

  Postoperative numerical pain rating scale (NRS) pain scores

  48 hours

• Postoperative analgesics administered

  Postoperative opioid utilization

  48 hours

Secondary Outcomes (3)

• Mobilization

  48 hours

• Time to readiness for discharge

  48 hours

• Complications

  48 hours

Study Arms (2)

SIFI local anesthesia

EXPERIMENTAL

Subjects randomized to the SiFi arm will have an ultrasound-guided suprainguinal fascia iliaca single shot block performed preoperatively in the anesthesia block room with 40ml of 0.2% ropivacaine local anesthetic. This will be reduced to 30 ml in patients under 60 kg.

Procedure: Regional anesthesia

FNB local anesthesia

ACTIVE COMPARATOR

Subjects randomized to the FNB arm will have an ultrasound-guided femoral nerve single shot block performed preoperatively in the anesthesia block room with 20ml of 0.5% ropivacaine local anesthetic. This will be reduced to 15ml in patients under 60 kg.

Procedure: Regional anesthesia

Interventions

Regional anesthesia PROCEDURE

ultrasound-guided suprainguinal fascia iliaca block with 40ml of ropivacaine local or ultrasound-guided femoral nerve block with 20ml of ropivacaine local anesthetic

FNB local anesthesia; SIFI local anesthesia

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18 or greater
• Having hip fracture surgery at the University of Alberta Hospital
• Suitable for multimodal analgesia including a peripheral nerve block

You may not qualify if:

• Contraindication to a nerve block technique
• Refuses consent for a nerve block technique

Sponsors & Collaborators

• University of Alberta: lead

Study Sites (1)

University of Alberta Hospital

Edmonton, Alberta, t6g2b7, Canada

Location

MeSH Terms

Conditions

Hip Fractures

Interventions

Anesthesia, Conduction

Condition Hierarchy (Ancestors)

Femoral Fractures; Fractures, Bone; Wounds and Injuries; Hip Injuries; Leg Injuries

Intervention Hierarchy (Ancestors)

Anesthesia; Anesthesia and Analgesia

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: Randomization will be conducted through blocked randomization with blocks of 4 according to a schedule not known to the investigators using a computerized algorithm. The attending surgeon, anesthetist, and nursing team will be blinded to the randomization assignment.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: A concealed-allocation parallel-group blinded randomized controlled clinical

Study Record Dates

• First Submitted: February 29, 2024
• First Posted: March 6, 2024
• Study Start: August 1, 2024
• Primary Completion: March 1, 2026
• Study Completion: March 1, 2026
• Last Updated: May 6, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)