Effects of Acupoint Massage Around Eyes on Ocular Biological Indexes

NCT06293196 | Recruiting

• 1 other identifier: 20231107
• Study Type: interventional
• Target: 55
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to investigate whether the acupoint eye exercise could impact the biological parameters of the eye.

Conditions

Investigating the Effects of Periocular Acupressure on Ocular Biological Indicators

Outcome Measures

Primary Outcomes (7)

• The effect of ocular acupoint massage on ocular blood flow.

  Ocular blood flow indicators were obtained using Optical Coherence Tomography (OCT).

  Ocular blood flow indicators were measured once at pre-intervention, immediately post-intervention, and at 10, 20, and 30 minutes post-intervention.

• The effect of ocular acupoint massage on intraocular pressure.

  Intraocular pressure (IOP) of patients was measured and recorded with the ICARE rebound tonometer.

  Intraocular pressure was measured once before the intervention and once immediately after the intervention.

• The effect of ocular acupoint massage on the diameter of Schlemm's canal.

  Imaging of the nasal and temporal corneoscleral regions of the right eye was performed using swept-source anterior segment optical coherence tomography (SS-AS-OCT). The diameter of Schlemm's canal was measured manually.

  Anterior segment imaging was performed once before and once immediately after the intervention to obtain the diameter values of Schlemm's canal.

• The effect of ocular acupoint massage on the area of Schlemm's canal.

  Imaging of the nasal and temporal corneoscleral regions of the right eye was performed using swept-source anterior segment optical coherence tomography (SS-AS-OCT). The area of Schlemm's canal was measured manually.

  Anterior segment imaging was performed once before and once immediately after the intervention to obtain the area values of Schlemm's canal.

• The effect of ocular acupoint massage on the width of the trabecular meshwork.

  Imaging of the nasal and temporal corneoscleral regions of the right eye was performed using swept-source anterior segment optical coherence tomography (SS-AS-OCT). The width of the trabecular meshwork was measured manually.

  Anterior segment imaging was performed once before and once immediately after the intervention to obtain the width values of the trabecular meshwork.

• The effect of ocular acupoint massage on the thickness of the trabecular meshwork.

  Imaging of the nasal and temporal corneoscleral regions of the right eye was performed using swept-source anterior segment optical coherence tomography (SS-AS-OCT). The thickness of the trabecular meshwork was measured manually.

  Anterior segment imaging was performed once before and once immediately after the intervention to obtain the thickness values of the trabecular meshwork.

• The effect of ocular acupoint massage on the tear film.

  The Keratograph was used to dynamically monitor the tear film break-up location and break-up time in a non-contact manner before and after the intervention, with tear meniscus height measured manually.

  The Keratograph was performed once before the intervention and once immediately after the intervention.

Secondary Outcomes (2)

• The effect of ocular acupoint massage on blood pressure.

  Blood pressure was measured once before the intervention and once immediately after it.

• The effect of ocular acupoint massage on heart rate.

  Heart rate was measured once before the intervention and once immediately after it.

Study Arms (4)

standard Chinese acupoint eye exercise group

EXPERIMENTAL

The volunteers performed a set of standard Chinese acupoint eye health exercises.

Other: acupressure

fake acupoint eye exercise group

EXPERIMENTAL

Volunteers performed a group of fake acupoint eye health exercises, the acupoint design in the place without acupoints.

Other: acupressure

simple eye closure group

NO INTERVENTION

The volunteers only closed their eyes and did not perform acupressure.

simple distance observation group

NO INTERVENTION

The volunteers only looked far without acupressure.

Interventions

acupressure OTHER

Massage acupoints and non-acupoint areas around the eyes.

fake acupoint eye exercise group; standard Chinese acupoint eye exercise group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• healthy people of all ages

You may not qualify if:

• presence of systemic diseases
• history of other eye diseases, surgeries, and/or medications, as well as eye trauma
• incomplete healing of the surgical site after eye surgery
• consumption of coffee, tea, or vasodilators within 6 hours before the commencement of the test

Sponsors & Collaborators

• Zhongnan Hospital: lead

Study Sites (1)

Zhongnan Hospital of Wuhan University

Wuhan, Hubei, 430000, China

RECRUITING

MeSH Terms

Interventions

Acupressure

Intervention Hierarchy (Ancestors)

Therapy, Soft Tissue; Musculoskeletal Manipulations; Complementary Therapies; Therapeutics; Physical Therapy Modalities; Rehabilitation

Central Study Contacts

Min Ke, doctor of medicine

CONTACT

18672395959; Keminyk@163.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 1, 2024
• First Posted: March 5, 2024
• Study Start: September 1, 2023
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): June 30, 2026
• Last Updated: January 21, 2026

Record last verified: 2026-01

Locations

CN (1)