Spleen Preserving Surgery for Splenic Hydatidosis: A Cohort Study on Short and Long-Term Outcomes

NCT06289816 | Completed

• 1 other identifier: 28/01/2023
• Study Type: observational
• Target: 18
• Locations: 1 country
• Sites: 1

Brief Summary

This retrospective cohort study examines the effectiveness of minimally invasive spleen-preserving surgeries compared to total splenectomy for treating primary splenic hydatidosis in Jordan. Covering 18 patients from January 2015 to June 2021, the research highlights similar recurrence rates between both surgical approaches, emphasizing the benefits of spleen preservation in maintaining immune function and reducing septic risks, particularly in pediatric patients.

Conditions

Spleen-Preserving Surgery; Echinococcus Granulosus Infection; Hydatid Disease; Minimally Invasive Surgery

Keywords

Spleen-Preserving Surgery; Primary Splenic Hydatid Cyst; Hydatid Disease; Minimally Invasive Surgery; Echinococcus granulosus; Recurrence

Outcome Measures

Primary Outcomes (2)

• Incidence of Postoperative Short-Term Complications

  The measure focuses on the incidence and nature of short-term complications following spleen-preserving surgeries compared to total splenectomy. Short-term complications may include infection, bleeding, or any other immediate post-surgical issues that impact recovery.

  Up to 1 month post-operation

• Incidence of Postoperative Long-Term Complications

  This measure assesses the long-term complications associated with spleen-preserving surgeries versus total splenectomy. Specifically, it examines the recurrence of hydatid cysts as a significant long-term complication.

  Up to 2 years post-operation

Interventions

Minimally Invasive Surgery PROCEDURE

Minimally Invasive Surgery : Laparoscopic partial splenectomy, cystectomy, and cyst deroofing.

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This retrospective study involved patients diagnosed with primary splenic hydatid cysts, from January 2015 to June 2021. The study included medical records of 18 patients aged 14 years or older, diagnosed exclusively with primary, non-recurrent splenic hydatid cysts. Exclusion criteria encompassed individuals under 14 years, patients in late pregnancy, those with recurrent cysts, extra-splenic involvement, or less than two years of postoperative follow-up.

You may qualify if:

• Adult patients (age 14 years or older).
• Diagnosed exclusively with primary, non-recurrent splenic hydatid cysts.

You may not qualify if:

• Children under 14 years of age.
• Patients in late pregnancy.
• Individuals with recurrent cysts.
• Cases with extra-splenic involvement.
• Patients with less than two years of postoperative follow-up.

Sponsors & Collaborators

• Yarmouk University: lead

Study Sites (1)

Anas Aljaiuossi

Irbid, 22110, Jordan

Location

MeSH Terms

Conditions

Echinococcosis; Recurrence

Interventions

Minimally Invasive Surgical Procedures

Condition Hierarchy (Ancestors)

Cestode Infections; Helminthiasis; Parasitic Diseases; Infections; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Surgical Procedures, Operative

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Consultant Hepatobiliary Surgeon

Study Record Dates

• First Submitted: February 24, 2024
• First Posted: March 4, 2024
• Study Start: January 1, 2015
• Primary Completion: June 30, 2021
• Study Completion: June 30, 2021
• Last Updated: March 4, 2024

Record last verified: 2024-02

Locations

JO (1)