Efficacy of Azadirachta Indica Based Herbal Mouthwash in Treating the Tooth Hypersensitivity

NCT06288776 | Completed

• 1 other identifier: SOD/ERB/2023/22-04
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

Type of study: Single-blinded clinical trial to evaluate the effectiveness of Azadirachta indica based Herbal mouthwash to treat the tooth sensitivity in patients. Participants aged 20 years and above having Gingival Index score 3 will be included in the study. Their tooth sensitivity will be checked initially and then they will be given Herbal based mouthwash for 3 months. Again, their tooth sensitivity shall be checked after 3 months.

Conditions

Tooth Sensitivity

Keywords

Azadirachta indica; Gingival Index; Herbal; Mouthwash; Tooth sensitivity

Outcome Measures

Primary Outcomes (1)

• Toothsensitivity declination with herbal based mouthwash

  Evaluation of herbal based mouth wash in eliminating the tooth sensitivity ranging between VAS scores 30-80.

  3 months

Study Arms (1)

Interventional Group

EXPERIMENTAL

Participants will be assessed for their tooth sensitivity (VAS scoring) and after giving herbal based mouthwash sensitivity will be assessed after 3 months

Diagnostic Test: Herbal based mouthwash

Interventions

Herbal based mouthwash DIAGNOSTIC_TEST

Herbal based mouthwash will be used to treat the tooth sensitivity in participants having VAS score values of tooth sensitivity ranging between 30-80

Interventional Group

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with good general health and no allergy
• Patients who have not used any mouthwash in last 3 month
• Study teeth shall be free of decay and restoration
• Study teeth shalll not be mobile
• Study teeth shall have the Gingival Index score 3
• Participants shall be able to read ,write and willing to give consent.

You may not qualify if:

• Patients with poor general health and allergies
• Patients who have used any mouthwash in last 3 months
• Teeth with decay and restorations
• Teeth with mobility
• Teeth with Gingival Index score more than 3
• Participants that wonn't be able to read ,write and willing to give consent.

Sponsors & Collaborators

• Pakistan Institute of Medical Sciences: lead

Study Sites (1)

Afsheen Mansoor

Islamabad, 44080, Pakistan

Location

Related Publications (1)

• Hall C, Sufi F, Milleman JL, Milleman KR. Efficacy of a 3% potassium nitrate mouthrinse for the relief of dentinal hypersensitivity: An 8-week randomized controlled study. J Am Dent Assoc. 2019 Mar;150(3):204-212. doi: 10.1016/j.adaj.2018.10.023.

  PMID: 30803493 BACKGROUND

MeSH Terms

Conditions

Dentin Sensitivity

Condition Hierarchy (Ancestors)

Tooth Diseases; Stomatognathic Diseases

Study Officials

• Afsheen Mansoor, PhD

  School of Dentistry, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad.

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Masking Details: Single-blinded study where participant will be masked.
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: In this study, participants will be selected by consecutive non-random sampling technique.

Study Record Dates

• First Submitted: February 24, 2024
• First Posted: March 1, 2024
• Study Start: February 1, 2023
• Primary Completion: April 30, 2023
• Study Completion: April 30, 2023
• Last Updated: March 1, 2024

Record last verified: 2024-02

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)