Preoperative Dextrose Infusion and Postoperative Nausea and Vomiting
The Relationship of Preoperative Intravenous Dextrose Infusion to Postoperative Nausea and Vomiting in Gynecological Laparoscopic and Hysteroscopic Surgeries: A Randomized Control Trial
1 other identifier
interventional
111
0 countries
N/A
Brief Summary
This research aims to investigate the efficacy of preoperative intravenous infusion of dextrose 5% during fasting in lowering the incidence and severity of post-operative nausea and vomiting related to laparoscopic gynaecologic procedures
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Mar 2024
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 25, 2024
CompletedFirst Posted
Study publicly available on registry
March 1, 2024
CompletedStudy Start
First participant enrolled
March 1, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2024
CompletedMarch 1, 2024
February 1, 2024
2 months
February 25, 2024
February 25, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
frequency of post-opertive nausea and vomiting in 24 hour
using verbal rating scale (VRS)
FROM ENROLLMENT TO 24 HOURS AFTER SURGERY
Secondary Outcomes (1)
TOTAL AMOUNT OF ANTIEMETIC REQUIRED
From end of surgery to 24 hours postoperative
Study Arms (3)
group c
NO INTERVENTIONcontrol group . this group will not receive any iv fluids
group d
EXPERIMENTALGroup D will receive 1 mL/kg/h 5% Dextrose infusion, applied preoperatively during fasting until induction of anesthesia
group r
ACTIVE COMPARATORthis group will receive 1 mL/kg/h ringer infusion, applied preoperatively during fasting until induction of anesthesia
Interventions
this group will receive 1 mL/kg/h 5% Dextrose infusion, applied preoperatively during fasting until induction of anesthesia
this group will receive 1 mL/kg/h ringer infusion, applied preoperatively during fasting until induction of anesthesia
Eligibility Criteria
You may qualify if:
- ASA physical status I and ll.
You may not qualify if:
- patients with a previous history of PONV.
- Patients with motion sickness, coagulopathy, diabetes mellitus, or severe hypertension
- patients with cardiac, renal or hepatic dysfunction.
- patients receiving an antiemetic agent within 24 h before surgery or cases where complications occurs during the surgery
- patients who have abnormal blood glucose on the night before surgery
- patients who are unable to understand and use the verbal rating scale (VRS);Growth developmental, and motor-mental retardation.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- assistant professor
Study Record Dates
First Submitted
February 25, 2024
First Posted
March 1, 2024
Study Start
March 1, 2024
Primary Completion
May 1, 2024
Study Completion
May 1, 2024
Last Updated
March 1, 2024
Record last verified: 2024-02