NCT06285851

Brief Summary

Female endurance athletes are susceptible to iron deficiency and this can impact their exercise performance. This study is a pilot trial to assess the tolerability of a novel iron supplement prior to conducting a clinical trial on the efficacy of the developed novel iron supplement on iron status and performance.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
14

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 23, 2023

Completed
19 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 12, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 12, 2023

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

January 30, 2024

Completed
1 month until next milestone

First Posted

Study publicly available on registry

February 29, 2024

Completed
Last Updated

March 28, 2024

Status Verified

March 1, 2024

Enrollment Period

19 days

First QC Date

January 30, 2024

Last Update Submit

March 26, 2024

Conditions

Outcome Measures

Primary Outcomes (2)

  • GI Symptoms

    Gastrointestinal Symptoms Questionnaire (rating scale 1-7 where 1= the absence of symptoms and 7=severe symptoms)

    Daily for 14 days

  • Gastrointestinal symptoms

    Patient-Reported Outcomes Measurement Information System (rating scale 0-4 where 0=Not at all, 1=A little bit, 2=Somewhat, 3=Quite a bit, 4=Very much)

    Weekly for 14 days

Secondary Outcomes (2)

  • Supplement Tolerability and Preferences Questionnaire

    14 days

  • Recovery

    14 days

Study Arms (1)

FeSC Cookie

EXPERIMENTAL

Iron-yeast complex

Dietary Supplement: FeSC

Interventions

FeSCDIETARY_SUPPLEMENT

Supplement

FeSC Cookie

Eligibility Criteria

Age18 Years - 25 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • cis-gendered female 18-25years old
  • BMI \<25 kg/m2
  • engaging in moderate to vigorous physical activity for ≥3 hours per week

You may not qualify if:

  • gastrointestinal issues (e.g. Irritable bowel disease/syndrome)
  • chronic illnesses
  • prescription medication (including oral contraceptives)
  • allergies to supplement ingredients
  • iron supplementation in the last 3 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Calgary

Calgary, Alberta, Canada

Location

Related Publications (1)

  • Shaw KA, Tompkins TA, Abrahamson-Durant B, MacNevin G, Parnell JA, MacInnis MJ, Reimer RA, Shearer J. Exploring tolerance and side effects of an innovative yeast-bound iron supplement: a feasibility trial. Pilot Feasibility Stud. 2025 Aug 15;11(1):110. doi: 10.1186/s40814-025-01690-w.

MeSH Terms

Conditions

ConstipationDiarrheaColic

Condition Hierarchy (Ancestors)

Signs and Symptoms, DigestiveSigns and SymptomsPathological Conditions, Signs and SymptomsInfant, Newborn, DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

  • Jane Shearer, PhD

    University of Calgary

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

January 30, 2024

First Posted

February 29, 2024

Study Start

November 23, 2023

Primary Completion

December 12, 2023

Study Completion

December 12, 2023

Last Updated

March 28, 2024

Record last verified: 2024-03

Data Sharing

IPD Sharing
Will not share

Locations