Femoral Blood Gas and Prediction of Postoperative Bleeding

NCT06285656 | Not Yet Recruiting

• 1 other identifier: ASH-KG
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Postoperative bleeding is still an important concern after major abdominal surgery. Postoperative bleeding is the most important determinant of morbidity and death. It results in longer hospital stays, the necessity for extra radiological tests, interventional radiology treatments, and the possibility of reoperation. Early detection of postoperative bleeding reduces morbidity and mortality with appropriate intervention.Simultaneous arterial and venous blood gas measurements can be used to quickly identify the degree of bleeding and the need for replacement in serious trauma patients brought to the emergency room.Lactate levels, venous oxygen saturation, and the differential in partial pressure of carbon dioxide between arterial and venous blood can all be used to indicate the requirement for replacement, as demonstrated in several studies. The purpose of this study is to evaluate lactate levels, venous oxygen saturation, and arterial-venous partial pressure of carbon dioxide difference in blood gas analysis in order to assess the severity of bleeding in patients undergoing major abdominal surgery as early as possible and perform replacement as soon as possible.

Conditions

Postoperative Hemorrhage; Blood Transfusion

Keywords

Abdominal Surgery; Postoperative Hemorrhage; Blood Transfusion

Outcome Measures

Primary Outcomes (1)

• Eritrocyte replacement

  could we predict eritrocyte replacement at early postoperative period?

  6 months

Secondary Outcomes (1)

• Postoperative Hemmorhagea

  6 months

Study Arms (2)

Group 1/

Patients with postoperative hemmorhagia

Grup 2

Patients without postoperative hemmorhagia

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients will have surgery at Ankara Bilkent City Hospital's General Surgery Clinic and then be transferred to the critical care unit.

You may qualify if:

• Patients with major abdominal surgery
• Postoperative intensive care unit following
• Accepting to participate in research

You may not qualify if:

• Age under 18 years old
• Pregnant patients
• Do not accept to participate of study

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Related Links

• Femoral blood gas analysis, another tool to assess hemorrhage severity following trauma: an exploratory prospective study
• Prognostic Significance of Blood Lactate and Lactate Clearance in Trauma Patients
• Changes in central venous saturation after major surgery, and association with outcome

Biospecimen

Retention: SAMPLES WITHOUT DNA

Blood gas

MeSH Terms

Conditions

Postoperative Hemorrhage

Condition Hierarchy (Ancestors)

Hemorrhage; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Postoperative Complications

Central Study Contacts

Hüseyin Fahri Martlı

CONTACT

+905301794699; fahri_martli@hotmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 3 Days
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 23, 2024
• First Posted: February 29, 2024
• Study Start: March 1, 2024
• Primary Completion: October 1, 2024
• Study Completion: October 3, 2024
• Last Updated: February 29, 2024

Record last verified: 2024-02

Data Sharing

• IPD Sharing: Will not share