STUDY OF THE EFFECT OF RHYTHMIC AND NON-RHYTHMIC MUSICAL PRIMING ON THE SYNTAX CAPACITY OF PRESBYACOUSTIC OLDER ADULTS

NCT06282601 | Recruiting

• 1 other identifier: GUIGOU - Defaye 2023
• Study Type: interventional
• Target: 27
• Locations: 1 country
• Sites: 1

Brief Summary

Presbyacusis, or age-related hearing loss, is a public health problem, affecting 20% of men and 30% of women over the age of 70 according to the WHO. In the most incapacitating cases, hearing aids are required. Numerous studies have evaluated the benefits of hearing aids, particularly in terms of improved hearing and quality of life. However, the specific effect of music on language skills has not yet been studied in hearing-impaired older adults. In this context, it was decided to study the effect of musical priming on the syntactic abilities of adults aged 70 or older with presbyacusis. This study is based on the hypothesis that music priming with regular music optimizes the syntax language skills of people with presbyacusis, as has already been proven in adults and normal-hearing children.

Conditions

Presbyacousie

Outcome Measures

Primary Outcomes (1)

• linguistic performance test focusing on syntax.

  At baseline

Study Arms (1)

Presbyacusis patients

EXPERIMENTAL

Other: Audiogram; Other: Musical priming for the syntax test; Other: Test MMSE; Other: Barcelona Music Reward Questionnaire

Interventions

Audiogram OTHER

Tonal and vocal free-field without lip-reading

Presbyacusis patients

Musical priming for the syntax test OTHER

Listening to music with a regular or irregular rhythm, then judging the grammaticality of 2x6 blocks of French sentences interrupted by a pause, each block presenting 4 sentences including 2 grammatically correct sentences and 2 grammatically incorrect sentences. The sentences are pronounced by a French female voice at a natural rhythm and comfortable volume.

Presbyacusis patients

Test MMSE OTHER

test to assess a person's cognitive functions and memory capacity.

Presbyacusis patients

Barcelona Music Reward Questionnaire OTHER

20 questions exploring 5 main facets of the musical reward experience, with 4 items for each of the 5 facets, for which participants indicate the level of agreement using a 5-level scale, ranging from "strongly disagree" to "strongly agree".

Presbyacusis patients

Eligibility Criteria

• Age: 70 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• No objection to participation in the study
• Men and women aged ≥ 70 years
• Patients diagnosed with presbyacusis (age-related bilateral and symmetrical sensorineural hearing loss, all stages combined), with or without the use of a bilateral hearing aid.
• If they use a hearing aid: hearing must have an average free-field fitted tonal threshold of 40 dB max and free-field fitted speech discrimination without lip-reading of 90-100% at 60dB in silence.
• MMSE score ≥ 24/30

You may not qualify if:

• Person under legal protection (curatorship, guardianship)
• Person under court order
• Adult unable to provide consent
• Person with a neurocognitive disorder (post-stroke, dyslexia, dyspraxia) or neuro-psychiatric disorder (dementia, autism)
• Severe sensorineural hearing loss with mean free-field threshold \> 40 dB and free-field speech discrimination without lip-reading of \< 90-100% at 60dB in silence
• Asymmetrical sensorineural hearing loss due to an additional cause of hearing loss on one side.
• Person with syntax disorder (discovery of sentence comprehension or production disorders during syntax test)

Sponsors & Collaborators

• Centre Hospitalier Universitaire Dijon: lead

Study Sites (1)

Chu Dijon Bourgogne

Dijon, 21000, France

RECRUITING

MeSH Terms

Interventions

Hearing

Intervention Hierarchy (Ancestors)

Vestibulocochlear Physiological Phenomena; Physiological Phenomena; Sensation; Nervous System Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Central Study Contacts

Alexis BOZORG-GRAYELI

CONTACT

03 80 29 37 58; alexis.bozorggrayeli@chu-dijon.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 19, 2024
• First Posted: February 28, 2024
• Study Start: August 2, 2025
• Primary Completion (Estimated): October 1, 2027
• Study Completion (Estimated): October 1, 2027
• Last Updated: February 12, 2026

Record last verified: 2026-02

Locations

FR (1)