Acute Myocardial Infarction in Cancer Patients

NCT06281054 | Active Not Recruiting

• 1 other identifier: SMC2023-12-027
• Study Type: observational
• Target: 4,500,000
• Locations: 1 country
• Sites: 1

Brief Summary

Using national health insurance service database, current study aim to evaluate the risk and prognosis of acute myocardial infarction in cancer patients and to find the optimal treatment strategy for acute myocardial infarction that can improve long-term prognosis.

Conditions

Acute Myocardial Infarction; Cancer

Keywords

Acute myocardial infarction; Cancer; Incidence; Prognosis

Outcome Measures

Primary Outcomes (1)

• All-cause death

  All-cause death which was obtained from death certification collected by Statistics Korea at the Ministry of Strategy and Finance of South Korea

  2-years after diagnosis of acute myocardial infarction

Secondary Outcomes (5)

• Myocardial infarction

  2-years after diagnosis of acute myocardial infarction

• Revascularization

  2-years after diagnosis of acute myocardial infarction

• Hospitalization for heart failure

  2-years after diagnosis of acute myocardial infarction

• Stroke

  2-years after diagnosis of acute myocardial infarction

• Clinically relevant bleeding

  2-years after diagnosis of acute myocardial infarction

Study Arms (2)

Revascularized Group

Cancer patients with diagnosis of acute myocardial infarction that was treated with PCI or CABG

Procedure: Revascularization

Medical Group

Cancer patients with diagnosis of acute myocardial infarction that was treated with medical treatment only

Interventions

Revascularization PROCEDURE

Performing PCI or CABG

Revascularized Group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who were diagnosed with cancer from 2002 to 2021 will be considered in the study. Among these patients, those diagnosed with acute myocardial infarction after the diagnosis with cancer will be included in the study.

You may qualify if:

• Patients diagnosed with cancer between 2002 and 2021
• Patients who were diagnosed with acute myocardial infarction after cancer diagnosis

You may not qualify if:

• Patients who died during period of cancer diagnosis

Sponsors & Collaborators

• Samsung Medical Center: lead
• Chonnam National University: collaborator

Study Sites (1)

Chonnam National University Hospital, Chonnam National University Medical School

Gwangju, South Korea

Location

MeSH Terms

Conditions

Neoplasms

Study Officials

• Joo Myung Lee, MD, MPH, PhD

  Samsung Medical Center

  PRINCIPAL INVESTIGATOR

• Seung Hun Lee, MD, PhD

  Chonnam National University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: February 20, 2024
• First Posted: February 28, 2024
• Study Start: January 1, 2002
• Primary Completion: December 31, 2021
• Study Completion: December 31, 2025
• Last Updated: March 14, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

KR (1)