Multi-disciplinary Care for Brain Metastases

NCT06280300 | Recruiting DMC

• 1 other identifier: UVMMC2203
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This is a health services intervention study aimed at understanding the impact of intensive multi-disciplinary care compared with standard care on patient-reported symptom outcomes and prognostic awareness in patients with brain metastases.

Conditions

Brain Metastases, Adult

Outcome Measures

Primary Outcomes (1)

• Patient reported outcomes

  Symptom burden based on patient reporting on Brain Mets Symptom Inventory

  6-12 months

Secondary Outcomes (3)

• Feasibility

  6-12 months

• Patient understanding of prognosis

  6-12 months

• survival

  6-12 months

Other Outcomes (1)

• Exploratory survival outcome

  6-12 months

Study Arms (2)

Standard of Care

ACTIVE COMPARATOR

Other: health services intervention

Multidisciplinary Care

EXPERIMENTAL

Other: health services intervention

Interventions

health services intervention OTHER

Health services intervention

Multidisciplinary Care; Standard of Care

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients of all genders must be at least 18 years of age.
• Patients must have histologically confirmed, newly diagnosed brain metastases from known or suspected solid tumor primary neoplasms.
• Patients must be able to accurately provide self-report data (e.g. per clinical judgment, cognitive function is intact).
• Patients must be able to complete questionnaires in English.
• Patients must have the ability to provide informed consent.

You may not qualify if:

• Patients who are \< 18 years of age are not eligible.
• Patients who are Pregnant are not eligible.

Sponsors & Collaborators

• University of Vermont Medical Center: lead

Study Sites (1)

University of Vermont Medical Center

Burlington, Vermont, 05401, United States

RECRUITING

MeSH Terms

Conditions

Brain Neoplasms

Condition Hierarchy (Ancestors)

Central Nervous System Neoplasms; Nervous System Neoplasms; Neoplasms by Site; Neoplasms; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Central Study Contacts

Alissa A Thomas, MD

CONTACT

802-847-8400; athoma21@med.uvm.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Neurological Sciences

Model Details: cohort study

Study Record Dates

• First Submitted: February 19, 2024
• First Posted: February 28, 2024
• Study Start: November 16, 2023
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): July 1, 2027
• Last Updated: January 29, 2026

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)