Adrenal Project: Clinical and Epidemiological Characterization of Adrenocortical Carcinoma in a Brazilian Cohort

NCT06279442 | Recruiting

• 1 other identifier: LACOG 0723
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 10

Brief Summary

This is a retrospective observational cohort study. The clinical, pathological and treatment data of participants identified with adrenocortical carcinoma from the year 2000 onwards will be evaluated. Participants recruited for this study will be identified at the participating sites.

Conditions

Carcinoma Adrenal; Carcinoma, Adrenocortical Recurrent

Keywords

Carcinoma adrenocortical

Outcome Measures

Primary Outcomes (2)

• Demographic Characterization of Adrenocortical Carcinoma in Brazil

  This measure aims to capture essential demographic attributes of individuals in Brazil diagnosed with adrenocortical carcinoma. It will include details such as age distribution in years, gender representation, geographic distribution, height in meters, weight in kilograms, as well as racial and ethnic demographics . These insights will contribute to a comprehensive understanding of the demographic landscape of adrenocortical carcinoma within the Brazilian population.

  Throughout the study period, an average of 18 months.

• Clinical Characterization of Adrenocortical Carcinoma in Brazil

  This measure aims to capture essential clinical attributes of individuals in Brazil diagnosed with adrenocortical carcinoma. It will include relevant clinical factors such as tumor stage, hormone secretion status, and treatment modalities. These insights will contribute to a comprehensive understanding of the clinical landscape of adrenocortical carcinoma within the Brazilian population.

  Throughout the study period, an average of 18 months.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Data will be included from 150 participants diagnosed with adrenocortical carcinoma who meet the study's inclusion and exclusion criteria. Data will be collected from the medical records of the included research sites throughout Brazil.

You may qualify if:

• Participants over 18 years old;
• Diagnosis of adrenocortical carcinoma with at least one clinical evaluation at the reference institution;
• Initial diagnosis or recurrence from the year 2000 onwards.

You may not qualify if:

• Participants with insufficient clinical or pathological data in the medical records.

Sponsors & Collaborators

• Latin American Cooperative Oncology Group: lead

Study Sites (10)

Pronutrir - Suporte Nutricional e Quimioterapia

Fortaleza, Ceará, 60.810-180, Brazil

RECRUITING

Hospital do Câncer do Maranhão Dr. Tarquínio Lopes Filho

São Luís, Maranhão, 65.015-460, Brazil

RECRUITING

Hospital Erasto Gaertner

Curitiba, Paraná, 81.520-060, Brazil

RECRUITING

Hospital Santa Joana Recife (Instituto Américas PE)

Recife, Pernambuco, 52.011-000, Brazil

RECRUITING

UOPECCAN - Hospital do Câncer de Cascavel

Cascavel, Santa Catarina, 85.806-300, Brazil

RECRUITING

FUNFARME - Hospital de Base de São José do Rio Preto

São José do Rio Preto, São Paulo, 15.090-000, Brazil

RECRUITING

INCA - Instituto Nacional de Câncer

Rio de Janeiro, 20.230-130, Brazil

RECRUITING

BP - A Beneficência Portuguesa de São Paulo

São Paulo, 01.323-030, Brazil

RECRUITING

HAOC - Hospital Alemão Oswaldo Cruz

São Paulo, 01.327-001, Brazil

RECRUITING

A.C. Camargo Cancer Center

São Paulo, 01.509-001, Brazil

RECRUITING

MeSH Terms

Conditions

Adrenal Cortex Neoplasms; Carcinoma

Condition Hierarchy (Ancestors)

Adrenal Gland Neoplasms; Endocrine Gland Neoplasms; Neoplasms by Site; Neoplasms; Adrenal Cortex Diseases; Adrenal Gland Diseases; Endocrine System Diseases; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type

Study Officials

• Milena Shizue Tariki

  Latin American Cooperative Oncology Group

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Giana Blume Corssac

CONTACT

+55 51 3384 5334; giana.corssac@lacogcancerresearch.org

Laura Voelcker

CONTACT

+55 51 3384 5334; laura.voelcker@lacogcancerresearch.org

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 19, 2024
• First Posted: February 28, 2024
• Study Start: October 9, 2024
• Primary Completion: August 25, 2025
• Study Completion: August 25, 2025
• Last Updated: February 12, 2025

Record last verified: 2025-02

Locations

BR (10)