Kidney Uptake at F-18 FDG PET/CT Studies and Renal Function Status

NCT06268067 | Not Yet Recruiting

• 1 other identifier: Renal uptake at F18 FDG PET/CT
• Study Type: observational
• Target: 97
• Locations: 0 countries
• Sites: N/A

Brief Summary

Searching for a possible correlation between renal uptake at F-18-FDG PET/CT and renal functional parameters in both normal subjects and patients with CKD.

Conditions

Renal Uptake at F-18-FDG PET/CT

Outcome Measures

Primary Outcomes (1)

• significance of renal uptake at F18-FDG PET CT studies

  The study assesses the significance of renal uptake at F18-FDG PET CT studies as regards Cr levels and EGFR.

  one year

Secondary Outcomes (1)

• Early detection of patients with CKD

  one year

Study Arms (2)

Chronic kidney diseased patiens

chronic kidney diseased patients

Device: PET/CT

Normal

normal subjects

Device: PET/CT

Interventions

PET/CT DEVICE

F-18 FDG PET/CT studies

Chronic kidney diseased patiens; Normal

Eligibility Criteria

• Age: 19 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients undergoing PET/CT examination for oncologic or non-oncologic purposes. For all the patients included in this study, data about serum Cr levels and estimated glomerular filtration rate (EGFR) calculated with the CKD-EPI formula.

You may qualify if:

• Adult patients undergoing PET/CT examination for oncologic or non-oncologic purposes.

You may not qualify if:

• Patients underwent PET/CT examination with age under 18 years.
• Presence of pathological conditions affecting kidneys (e.g., cancers, inflammation, polycystic kidney disease)
• Inability to stay still for the duration of the scan.
• Claustrophobia.
• Patients with uncontrolled diabetics (blood glucose \>200 mg/dl immediately before PET/CT scan)
• Pregnant females.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (2)

• Dondi F, Pisani AR, Lucarelli NM, Gazzilli M, Talin A, Albano D, Rubini D, Maggialetti N, Rubini G, Bertagna F. Correlation between Kidney Uptake at [18F]FDG PET/CT and Renal Function. J Pers Med. 2023 Dec 28;14(1):40. doi: 10.3390/jpm14010040.

  PMID: 38248741 RESULT

• Ammirati AL. Chronic Kidney Disease. Rev Assoc Med Bras (1992). 2020 Jan 13;66Suppl 1(Suppl 1):s03-s09. doi: 10.1590/1806-9282.66.S1.3.

  PMID: 31939529 RESULT

MeSH Terms

Interventions

Positron Emission Tomography Computed Tomography

Intervention Hierarchy (Ancestors)

Positron-Emission Tomography; Tomography, Emission-Computed; Image Interpretation, Computer-Assisted; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Tomography, X-Ray Computed; Multimodal Imaging; Radiographic Image Enhancement; Image Enhancement; Photography; Radiography; Tomography, X-Ray; Radionuclide Imaging; Tomography; Diagnostic Techniques, Radioisotope

Central Study Contacts

Rana M Farghali, Master

CONTACT

01014491926; drrana.m.f@aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Target Duration: 6 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Rana Mahmoud Farghali

Study Record Dates

• First Submitted: February 13, 2024
• First Posted: February 20, 2024
• Study Start: March 1, 2024
• Primary Completion: March 1, 2025
• Study Completion: April 1, 2025
• Last Updated: February 20, 2024

Record last verified: 2024-02