NCT06266949

Brief Summary

The purpose of this study is to assess wether the SONDA visual field test is suitable for patients with a supra sellar tumour.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
3mo left

Started Aug 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress77%
Aug 2025Aug 2026

First Submitted

Initial submission to the registry

January 25, 2024

Completed
26 days until next milestone

First Posted

Study publicly available on registry

February 20, 2024

Completed
1.4 years until next milestone

Study Start

First participant enrolled

August 1, 2025

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2026

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2026

Expected
Last Updated

May 2, 2025

Status Verified

May 1, 2024

Enrollment Period

8 months

First QC Date

January 25, 2024

Last Update Submit

May 1, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • Convert validity

    Difference (dB) between the predicted MD (SONDA) and the assessed MD (SAP), expressed as delta MD.

    Baseline

  • Test-retest reliability

    The variability of the predicted MD (dB) between consecutive measurements in the same person.

    baseline 1, baseline 2, 6-8 weeks post-operative

Secondary Outcomes (1)

  • Experience

    Baseline

Study Arms (2)

Patients

Participants will undergo a visual acuity test. Next they will perform the SONDA test 2 times at one visit and once more in a later visit Participants will fill in a questionnaire

Diagnostic Test: SONDA

Healthy controls

Participants will perform the SONDA test 2 times

Diagnostic Test: SONDA

Interventions

SONDADIAGNOSTIC_TEST

Perimetry based visualfield analysis

Healthy controlsPatients

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with a (supra)sellar tumour and healthy controls

You may qualify if:

  • Diagnosed with a (supra)sellar tumor
  • Visual field loss based on the most recent SAP; False positive rate \<15%; fixation losses \<20%
  • Informed written consent

You may not qualify if:

  • Neurological disorders
  • Eye disease not related to a (supra)sellar tumor

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UMCG

Groningen, Provincie Groningen, 9713 GZ, Netherlands

Location

MeSH Terms

Conditions

Pituitary NeoplasmsHemianopsia

Condition Hierarchy (Ancestors)

Endocrine Gland NeoplasmsNeoplasms by SiteNeoplasmsHypothalamic NeoplasmsSupratentorial NeoplasmsBrain NeoplasmsCentral Nervous System NeoplasmsNervous System NeoplasmsBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesHypothalamic DiseasesPituitary DiseasesEndocrine System DiseasesVision DisordersSensation DisordersNeurologic ManifestationsBlindnessEye DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Jos MA Kuijlen, MD/PHD

    University Medical Center Groningen

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jos MA Kuijlen, MD/PHD

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 25, 2024

First Posted

February 20, 2024

Study Start

August 1, 2025

Primary Completion

April 1, 2026

Study Completion (Estimated)

August 1, 2026

Last Updated

May 2, 2025

Record last verified: 2024-05

Locations