Hand Exercises in Psoriatic Arthritis

NCT06263634 | Completed

• 1 other identifier: 2022-206
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

This study is a randomized controlled study examining the effects of 8-week hand home exercises on grip strength, functionality, disease activity and quality of life in patients with PsA. Individuals participating in the study will be randomly divided into 2 groups. Individuals in the intervention group will perform home exercises consisting of stretching, mobility and strengthening, 4 days a week for 8 weeks, and the patients' compliance with the exercise will be monitored by phone call once a week. Individuals in the control group are on the waiting list and the same home exercise program will be taught to the patients at the end of the study.

Conditions

Psoriatic Arthritis; Hand Rheumatism

Keywords

Psoriatic Arthritis; hand exercises; grip strength; functionality; disease activity; quality of life

Outcome Measures

Primary Outcomes (3)

• Psoriatic Arthritis Disease Activity Score (DAPSA)

  DAPSA; It is a composite measurement focused on peripheral arthritis, developed for reactive arthritis, adapted to PsA patients and frequently used, evaluating disease activity and response to treatment in clinical studies. There are four components of score including the parameters a) tender joint count (68 joints), b) swollen joint count (66 joints), c) CRP value (mg/l) and d) patient's disease activity and pain assessment (with a 10 cm visual analog scale). DAPSA scores are calculated by summing each of these components. Cut-off values for disease activity; A score of \<4 was determined as remission, a score of \<14 was determined as minimal disease activity, a score of \<28 was determined as moderate disease activity, and a score of 28 was determined as high degree of disease activity.

  8 weeks

• Hand grip strength measurement

  Hand grip strength will be measured with a Jamar hydraulic hand dynamometer (Sammons Preston, USA). Grip tests will be performed in the standard position recommended by the American Association of Hand Therapists. This is the standard position; The patient is seated in a position that provides 90-20 degree flexion of the hip and knee, shoulder adduction, forearm neutral position, 90 degree flexion of the elbow, 0-30 degree extension of the wrist and 0-15 degree ulnar deviation. The measurement will be repeated three times. There will be a 15-second rest break at the end of each measurement. As a result, the average of three measurements will be recorded.

  8 weeks

• Hand fine grip strength measurement:

  Fine grip strength measurements will be made with finger dynamometry (Pinchmeter-Sammons Preston, USA). Grip tests will be performed in the standard position recommended by the American Association of Hand Therapists. This is the standard position; The patient is seated in a position that provides 90 degrees of hip and knee flexion, shoulder adduction, forearm neutral position, 90 degree flexion of the elbow, 0-30 degree extension of the wrist and 0-15 degree ulnar deviation. Three different finger grips will be evaluated. These: 1- Fingertip grip strength, 2- Lateral grip strength, 3- Three point grip strength. Measurements will be repeated three times. There will be a 15-second rest break at the end of each measurement. As a result, the average of three measurements will be recorded.

  8 weeks

Secondary Outcomes (5)

• Nine-Hole Peg Test

  8 weeks

• Duruöz Hand Index

  8 weeks

• Michigan Hand Outcome Questionnaire (MHQ)

  8 weeks

• Hand Functional Index (HFI)

  8 weeks

• Psoriatic Arthritis Quality of Life Questionnaire (PsAQoL)

  8 weeks

Study Arms (2)

Home exercises group

EXPERIMENTAL

The intervention group will perform 30-45 minutes of home exercises consisting of stretching, mobility and strengthening, 4 days a week for 8 weeks, and the patients' compliance with the exercise will be monitored by phone call once a week.

Other: Hand exercises

Control group

NO INTERVENTION

Patients in the control group will be on the waiting list and will be taught hand exercises when the program ends.

Interventions

Hand exercises OTHER

30-45 minutes of home exercises consisting of stretching, mobility and strengthening

Home exercises group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Being diagnosed with PsA by a physician according to CASPAR criteria
• Being 18 years or older
• Involvement in hand joints (pain, swelling, tenderness)
• Being on stable drug treatment for the last 6 months
• Having sufficient cooperation to participate in the study
• Volunteering to participate in the study

You may not qualify if:

• Having difficulty cooperating at work
• Having additional orthopedic and/or neurological disease that will affect hand functions

Sponsors & Collaborators

• Akdeniz University: lead

Study Sites (1)

Akdeniz University

Antalya, Turkey (Türkiye)

Location

Related Publications (1)

• Candiri B, Talu B, Demirtas Karaoba D, Ozaltin GE, Yolbas S. Effect of psoriatic arthritis on the strength, proprioception, skill, coordination, and functional condition of the hand. Int J Rheum Dis. 2022 Jan;25(1):47-55. doi: 10.1111/1756-185X.14241. Epub 2021 Nov 24.

  PMID: 34821039 RESULT

Related Links

• full text

MeSH Terms

Conditions

Arthritis, Psoriatic

Condition Hierarchy (Ancestors)

Spondylarthropathies; Spondylarthritis; Spondylitis; Spinal Diseases; Bone Diseases; Musculoskeletal Diseases; Arthritis; Joint Diseases; Psoriasis; Skin Diseases, Papulosquamous; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Sebahat Yaprak Cetin, PhD

  Akdeniz University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Randomized controlled trial

Study Record Dates

• First Submitted: February 9, 2024
• First Posted: February 16, 2024
• Study Start: April 5, 2023
• Primary Completion: April 5, 2024
• Study Completion: April 5, 2024
• Last Updated: June 10, 2024

Record last verified: 2024-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)