Trials Sponsors Conditions Drugs Pricing

Conditions

Drug Reaction With Eosinophilia and Systemic Symptom Drug-Induced Rash Maculopapular Exanthem Stevens-Johnson Syndrome Vitamin D Deficiency

Keywords

vitamin DStevens-Johnson SyndromeDrug Reaction with Eosinophilia and Systemic SymptomMaculopapular ExanthemDrug AllergyDrug Hypersensitivity

Outcome Measures

Primary Outcomes (1)

Serum vitamin D levels
Serum vitamin D levels at baseline
At baseline

Study Arms (4)

1. Patients diagnosed with drug-induced severe non-immediate cutaneous reactions

Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), drug reaction with eosinophilia and systemic symptom (DRESS), acute generalized exanthematous pustulosis (AGEP)

2. Patients diagnosed with drug-induced non-severe non-immediate cutaneous reactions

Maculopapular exanthem (MPE), fixed drug eruption (FDE)

3. Subjects who tolerated drugs potentially causing severe non-immediate cutaneous reactions

Studied drug groups matched patients in group 1

4. Subjects who tolerated drugs potentially causing non-severe non-immediate cutaneous reactions

Studied drug groups matched patients in group 2

Eligibility Criteria

Age15 Years+

Sexall

Healthy VolunteersNo

Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Cases: Subjects who develop drug-induced non-immediate cutaneous reactions Controls: subjects who can tolerate similar drug groups without allergic reactions

You may qualify if:

Diagnosed with SJS/TEN, DRESS, AGEP, MPE, or FDE as mentioned above

Sponsors & Collaborators

Chulalongkorn University
Otherlead

Study Sites (1)

Faculty of Medicine, Chulalongkorn University

Bangkok, 10330, Thailand

MeSH Terms

Conditions

Stevens-Johnson SyndromeDrug Hypersensitivity SyndromeDrug EruptionsVitamin D DeficiencyDrug Hypersensitivity

Condition Hierarchy (Ancestors)

StomatitisMouth DiseasesStomatognathic DiseasesDermatitisSkin DiseasesSkin and Connective Tissue DiseasesErythema MultiformeErythemaSkin Diseases, VesiculobullousHypersensitivity, Delayed

Study Officials

Jettanong klaewsongkram, MD
Chulalongkorn University
PRINCIPAL INVESTIGATOR

Enrollment

120 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: CASE CONTROL
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

February 9, 2022

First Posted

February 16, 2024

Study Start

May 30, 2021

Actual (reported)

Vitamin D Levels in Non-immediate Drug Hypersensitivity Case-control Study

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Study Arms (4)

1. Patients diagnosed with drug-induced severe non-immediate cutaneous reactions

2. Patients diagnosed with drug-induced non-severe non-immediate cutaneous reactions

3. Subjects who tolerated drugs potentially causing severe non-immediate cutaneous reactions

4. Subjects who tolerated drugs potentially causing non-severe non-immediate cutaneous reactions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Study Arms (4)

1. Patients diagnosed with drug-induced severe non-immediate cutaneous reactions

2. Patients diagnosed with drug-induced non-severe non-immediate cutaneous reactions

3. Subjects who tolerated drugs potentially causing severe non-immediate cutaneous reactions

4. Subjects who tolerated drugs potentially causing non-severe non-immediate cutaneous reactions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations