NCT06260930

Brief Summary

The main aim of this study is to detect the value of transthoracic ultrasonography in the diagnosis and assessment of ILDs in correlation to chest X- ray, blood gases, pulmonary function test and echocardiography and to compare it with high resolution CT (HRCT) as a golden diagnostic investigation.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2017

Typical duration for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2017

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2019

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
4.1 years until next milestone

First Submitted

Initial submission to the registry

January 9, 2024

Completed
1 month until next milestone

First Posted

Study publicly available on registry

February 15, 2024

Completed
Last Updated

February 15, 2024

Status Verified

February 1, 2024

Enrollment Period

2.7 years

First QC Date

January 9, 2024

Last Update Submit

February 13, 2024

Conditions

Interstitial Lung Disease

Outcome Measures

Primary Outcomes (1)

  • Sensitivity and specificity of the lung sonography for interstitial lung disease screening

    To estimate the sensitivity and specificity of the lung sonography for interstitial disease screening in comparison with HRCT. \[Time Frame: 12 months\]

    12 months

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Eligible patients will be recruited from the Department of Chest, Aswan University Hospital

You may qualify if:

  • Adults (≥18 years) diagnosed with ILD
  • All patients must fulfil the 2018 criteria for HRCT chest finding for the diagnosis of Usual interstitial pneumonia (UIP) form

You may not qualify if:

  • Patients with cardiac diseases (Left-sided Heart failure, pulmonary edema) \[they may have findings of multiple B lines on transthoracic ultrasound examination which mimic ILD findings\].
  • Patients with chronic kidney diseases (as patients presented with nephrogenic pulmonary edema may have findings of multiple B lines on transthoracic ultrasound examination which mimic ILD findings).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Deconinck B, Verschakelen J, Coolen J, Verbeken E, Verleden G, Wuyts W. Diagnostic workup for diffuse parenchymal lung disease: schematic flowchart, literature review, and pitfalls. Lung. 2013 Feb;191(1):19-25. doi: 10.1007/s00408-012-9433-5. Epub 2012 Nov 13.

    PMID: 23149802BACKGROUND

MeSH Terms

Conditions

Lung Diseases, Interstitial

Condition Hierarchy (Ancestors)

Lung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate professor

Study Record Dates

First Submitted

January 9, 2024

First Posted

February 15, 2024

Study Start

January 1, 2017

Primary Completion

September 1, 2019

Study Completion

December 1, 2019

Last Updated

February 15, 2024

Record last verified: 2024-02