Medial Patellofemoral Ligament Reconstruction in Children - a 2-8 Years Follow-up Study

NCT06257836 | Active Not Recruiting DMC

• 1 other identifier: Danish EC: 1-10-72-299-21
• Study Type: observational
• Target: 160
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this project is to investigate the treatment outcome after MPFL reconstruction in children as a treatment for chronic patellar instability, where the superficial part of the quadriceps tendon is fixed to the femur with anchors. The outcome will be compared with a healthy cohort matched on age and gender.

Conditions

Medial Patellofemoral Dislocation; Medial Patellofemoral Ligament Reconstruction

Keywords

MPFL, Knee, Medial Patellofemoral Ligament, Surgery

Outcome Measures

Primary Outcomes (1)

• Kujala (Anterior Knee Pain Scale)

  Patient reported outcome score, 0=worst and 100=best

  24 month

Secondary Outcomes (9)

• Donor site morbidity score, 0=worst and 100=best

  24 month

• Numerical Rating Scale (NRS-pain score)

  24 month

• Tegner (Activity Score)

  24 month

• Knee pain

  24 month

• One-legged single hop for distance

  24 month

Study Arms (2)

MPFL reconstruction with quadriceps graft

Children with medial patellofemoral reconstruction operated with epiphyses sparing quadriceps technique from 2016-2022.

Other: MPFL-reconstruction

Healthy Cohort

A healthy cohort matched on age (+/- 2 years) and gender

Interventions

MPFL-reconstruction OTHER

Children with patella dislocations are operated from 2016-2022 with a quadriceps knee cap stabilization technique.

MPFL reconstruction with quadriceps graft

Eligibility Criteria

• Age: 14 Years - 23 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients who have undergone MPFL quadriceps surgery as children in the period 2016-2022 at Aarhus University Hospital and have more than 2 years of follow-up. The patients will be 14-23 years old at the time of referral.

You may qualify if:

• MPFL-reconstruction with Quadriceps tendon graft
• Open physis at surgery date
• Minimum 2 years Follow up

You may not qualify if:

• More surgeries in index knee
• MPFL-r in opposite knee
• MPFL revision in index knee
• No knee problems
• None
• No knee problems

Sponsors & Collaborators

• Aarhus University Hospital: lead

Study Sites (1)

Division of Sports Trauma, Palle Juul-Jensens Boulevard 99

Aarhus N, 8200, Denmark

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor, PhD, MD

Study Record Dates

• First Submitted: February 6, 2024
• First Posted: February 14, 2024
• Study Start: March 1, 2024
• Primary Completion: December 31, 2025
• Study Completion (Estimated): June 1, 2026
• Last Updated: October 1, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

DK (1)