NCT06254768

Brief Summary

To study if continuous glucose monitors are feasible for use in children and adolescents with obesity.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2023

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 17, 2023

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 27, 2023

Completed
12 months until next milestone

First Posted

Study publicly available on registry

February 12, 2024

Completed
18 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2024

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2024

Completed
Last Updated

February 12, 2024

Status Verified

February 1, 2024

Enrollment Period

1.1 years

First QC Date

February 27, 2023

Last Update Submit

February 8, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Feasibility of continuous glucose monitor(CGM) use in children and adolescents with obesity

    Investigator will measure this outcome using recruitment rate achieved each month for the duration of the study period as the number of participants screened per month over the number of participants consented.

    6 weeks

Secondary Outcomes (1)

  • To access the change in glycemic variability measured by CGMS in unblinded versus blinded periods through standard deviation of the mean.

    6 weeks

Other Outcomes (5)

  • Effect of on sleep in youth with obesity using CGMs

    6 weeks

  • Effect of CGM use on physical activity in youth with obesity when using CGMs

    6 weeks

  • Effect of CGM use on dietary intake in youth with obesity when using CGMs

    6 weeks

  • +2 more other outcomes

Study Arms (2)

Unblinded

EXPERIMENTAL

They will wear the device and have access to their data- UNBLINDED ARM

Device: Continuous glucose monitor

Blinded

EXPERIMENTAL

They will wear the device but will not have access to their data- BLINDED ARM

Device: Continuous glucose monitor

Interventions

its a device used to measure glucose from interstitial fluids and provides feedback regarding the same every 5 minutes.

BlindedUnblinded

Eligibility Criteria

Age10 Years - 21 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Age 10-21 years BMI \>95th percentile

You may not qualify if:

  • Previous diagnosis of Prader Willi Syndrome or hypothalamic obesity
  • Intellectual disability
  • Previous or planned bariatric surgery
  • Hemoglobin A1c \>6.5 %
  • Current use of medication that impacts weight

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pediatric Endocrinology Division, University of California

Los Angeles, California, 90025, United States

RECRUITING

MeSH Terms

Conditions

Pediatric Obesity

Condition Hierarchy (Ancestors)

ObesityOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Steven D Mittelman, MD, PhD

    University of California, Los Angeles

    STUDY DIRECTOR

Central Study Contacts

Sri Nikhita Chimatapu, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

February 27, 2023

First Posted

February 12, 2024

Study Start

January 17, 2023

Primary Completion

March 1, 2024

Study Completion

June 1, 2024

Last Updated

February 12, 2024

Record last verified: 2024-02

Data Sharing

IPD Sharing
Will not share

Locations