Study Stopped
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Comparison of Free Gingival Graft and Modified Apical Repositioning Flap Techniques
1 other identifier
interventional
15
1 country
1
Brief Summary
Attached gingiva, a crucial component of the keratinized tissue, plays a vital role in preserving periodontal health. The free gingival graft (FGG) and modified apically repositioned flap (MARF) techniques are frequently used for addressing issues related to insufficient attached gingiva. The aim of this study was to compare the efficiency of the FGG and the MARF increasing the zone of attached gingiva in 2-year posttreatment.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Feb 2019
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 15, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 22, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2023
CompletedFirst Submitted
Initial submission to the registry
February 2, 2024
CompletedFirst Posted
Study publicly available on registry
February 12, 2024
CompletedFebruary 13, 2024
February 1, 2024
3.8 years
February 2, 2024
February 10, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Attached gingiva width
The width of the attached gingiva was calculated by measuring the distance from the crest of the gingival margin to the mucogingival junction and then subtracting the probing depth of the gingival sulcus from this distance on the particular tooth.
Baseline, third month, first year and second years.
Keratinized tissue width
The width of the keratinized tissue was calculated by measuring the distance from the crest of the gingival margin to the mucogingival junction
Baseline, third month, first year and second years.
Secondary Outcomes (1)
Pocket probing depth
Baseline, third month, first year and second years.
Study Arms (3)
Patient selection
OTHERA total of 15 (female) patients, between 31 and 70 years, who were systemically and periodontally healthy and applied to the periodontology clinic for treatment, were included in our study. Criteria for inclusion in the study are having ≥15 permanent teeth excluding third molars, not using any orthodontic appliance, not being pregnant or breastfeeding, not having any uncontrolled chronic and/or auto-immune disease, and not smoking.
MARF and FGG tehcniques
OTHERFree gingival graft for the treatment of a total of 21 teeth with gingival recession in the lower jaw incisors area, no bone dehiscence, and the amount of attached gingiva being at least 0.5 mm and at most 1.5 mm and modified apically positioned flap methods were randomly selected (coin toss) and applied by a single investigator (MY). Surgical methods were performed on a minimum of 1 and a maximum of 2 teeth in the treated areas.
Post-surgical evalution and periodontal measurements
OTHERClinical periodontal parameters (plaque index (PI), pocket probing depth (PPD), bleeding on probing (BOP), gingival recession (GR) and clinical attachment level (CAL)) were recorded and evaluated at baseline, third months, first and second years. Periodontal measurements (keratinized tissue width (KTW), attached gingiva width (AGW)) recorded and evaluated at baseline, third months, first and second years.
Interventions
Patient selection were selected according to selected criteria.
Following the operations, periodontal measurements were measured at the baseline, third month, first and second years.
Eligibility Criteria
You may qualify if:
- having ≥15 permanent teeth excluding third molars,
- not using any orthodontic appliance,
- not being pregnant or breastfeeding,
- not having any uncontrolled chronic and/or auto-immune disease,
- not smoking.
You may not qualify if:
- having chronic and/or auto-immune disease
- smoking.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Istanbul Medipol University, School of Dentistry
Istanbul, Fatih, 34083, Turkey (Türkiye)
Related Publications (2)
Carnio J, Camargo PM, Klokkevold PR, Pirih FQ. The Modified Apically Repositioned Flap Technique: A Long-Term (4 to 16 Years) Retrospective Study. Int J Periodontics Restorative Dent. 2018 July/August;38(4):519-524. doi: 10.11607/prd.3028. Epub 2017 Dec 15.
PMID: 29244886BACKGROUNDCarnio J, Carnio AT, Pirih FQ, Cordero MG, Camargo PM. The Modified Apically Repositioned Flap Technique and Its Potential to Create Attached Gingiva in Areas with No Keratinized Tissue: A Long-Term (1 to 11 Years) Retrospective Case Series Study. Int J Periodontics Restorative Dent. 2020 Jan/Feb;40(1):103-109. doi: 10.11607/prd.4241.
PMID: 31815979BACKGROUND
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Masking Details
- double (Participant, Investigator)
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Prof Dr
Study Record Dates
First Submitted
February 2, 2024
First Posted
February 12, 2024
Study Start
February 15, 2019
Primary Completion
November 22, 2022
Study Completion
December 1, 2023
Last Updated
February 13, 2024
Record last verified: 2024-02
Data Sharing
- IPD Sharing
- Will not share
IPD will not be shared