Evaluation of Fluid Responsiveness With Recruitment Maneuver After Sternotomy in Coronary Artery Bypass Surgery

NCT06249568 | Recruiting

• 1 other identifier: E2-23-3460
• Study Type: observational
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

Assuming that the basic reliability of dynamic indices will increase with the application of functional hemodynamic tests after sternotomy and protective lung ventilation in patients undergoing elective coronary artery bypass surgery, it is useful to predict fluid responsiveness after sternotomy in coronary artery bypass surgery patients ventilated with 6 ml/kg PBW (ideal body weight). We aimed to reveal the sensitivity and specificity of PPV and SVV changes by applying a lung opening maneuver.

Conditions

Fluid Therapy; Coronary Artery Bypass Surgery Patients; Lung Recruitment Maneuver

Keywords

fluid therapy; Coronary Artery Bypass Surgery Patients; Lung Recruitment Maneuver

Outcome Measures

Primary Outcomes (1)

• Determination of fluid responsiveness in patients undergoing coronary arter bypass surgery.

  : Demonstration of fluid responsiveness in patients who will undergo coronary artery bypass surgery will prevent unnecessary fluid administration in case of hemodynamic disturbance, and medical treatments and interventions can be performed in a timely and targeted manner. Researchers will perform a recruitment maneuver on the patients and record mean arterial pressure and stroke volume index. Researchers will perform a recruitment maneuver on the patients and record mean arterial pressure and stroke volume index. Afterwards, researchers will give 3ml/cc balanced fluid to the patient and record the change in mean arterial pressure and stroke volume index.

  from start to 4 months

Study Arms (1)

patients who will have coroner arter bypass surgeon

Patients undergoing coronary artery bypass surgery will be eliminated if there are exclusion criteria. Patients who do not have exclusion criteria will be included in the study if they agree to volunteer.

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

ASA2-3 patients between the ages of 18-80 who will undergo elective coronary bypass surgery under general anesthesia

You may qualify if:

• ASA2-3 patients between the ages of 18-80 who will undergo elective coronary bypass surgery under general anesthesia

You may not qualify if:

• \. Be younger than 18 years old, be over 80 years old
• \. Patients with an ASA score greater than 3
• \. EF\<40%
• \. Those with contraindications to anesthetic drugs
• \. Patients with BMI\>30
• \. Patients who did not want to participate in the study
• \. Right ventricular dysfunction
• \. COPD(Chronic obstructive pulmonary disease)
• \. Bullous lung disease
• \. Moderate to severe PHT
• \. Severe kidney or liver disease
• \. Patients with hemodynamic instability in the perioperative period
• \. Pregnancy

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Study Sites (1)

Ankara Bilkent Şehir Hastanesi

Ankara, 06800, Turkey (Türkiye)

RECRUITING

Central Study Contacts

meltem sakman yılmaz

CONTACT

+90 505 922 1049; meltemsakmann@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant doctor

Study Record Dates

• First Submitted: January 13, 2024
• First Posted: February 8, 2024
• Study Start: June 1, 2023
• Primary Completion: August 2, 2024
• Study Completion: August 20, 2024
• Last Updated: July 16, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)