The Effects of Supervised Aerobic Training on Dyslipidemia Among Diabetic Older Patients

NCT06246435 | Completed

• 1 other identifier: RRC-2014-010
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

In this study, we are trying to explore the potential effects of moderate aerobic exercise for six months on the severity values of blood sugar, HbA1c, insulin, lipid profile, and highly sensitive CRP (hs-CRP) in a total of 50 subjects diagnosed with diabetes for more than five years with an age range of 30-70 years.

Conditions

Diabetes Mellitus; Exercise

Outcome Measures

Primary Outcomes (2)

• Assessment of body weight, and height as anthropometric measurements

  In this test we are trying to explorer the effects of exercise training on anthropometric parameter's. Thus, weight, and height, and standardized measurements of weight and height were taken in light clothing without shoes for all patient groups

  6 month

• Assessment of body mass index ( BMI in kg/m^2)as anthropometric measurements

  In this test, BMI from body weight and height measurements for each participant were estimated before and after exercise training interventions by using a bioelectrical impedance analysis (BIA) based body composition analyzer (TBF 105, Tanita Corporation, Tokyo, Japan)

  6 month

Secondary Outcomes (2)

• Analysis of diabetic control parameters

  6 month

• estimation of lipid profile

  6 month

Study Arms (2)

Prediabetic group

The prediabetic group (HbA1c ≤ 6.5, n = 25)

Other: moderate aerobic exercise

T2MD group

(HbA1c ≥ 6.5, n = 25).

Other: moderate aerobic exercise

Interventions

moderate aerobic exercise OTHER

Prediabetic group; T2MD group

Eligibility Criteria

• Age: 30 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Fifty participants aged 30-70 years diagnosed with type 2 diabetes (DM2) for more than 5 years according to the American Diabetes Association criteria were invited to this study. Based on ADA criteria, the subjects were classified according to the level of glycated hemoglobin (HbA1c) into two groups; the prediabetic group (HbA1c ≤ 6.5, n=25) and the diabetic group (HbA1c ≥ 6.5, n=25).

You may qualify if:

• diagnosed with type 2 diabetes (DM2) for more than 5 years according to the American Diabetes Association criteria

You may not qualify if:

• Patients with a history of smoking, abnormal alcohol intake, anemia, overt complications of diabetes like nephropathy, neuropathy, retinopathy, and other heart complications, and are suffering from viral infections, chronic liver disease, hypothyroidism, and drugs (diuretics; oral contraceptives) were excluded from this study

Sponsors & Collaborators

• King Saud University: lead

Related Publications (1)

• Alghadir AH, Gabr SA, Iqbal A. The effects of supervised aerobic training on dyslipidaemia among diabetic older patients. BMC Endocr Disord. 2024 Oct 9;24(1):212. doi: 10.1186/s12902-024-01745-8.

  PMID: 39385223 DERIVED

Biospecimen

Retention: SAMPLES WITHOUT DNA

For all participants, standardized physical examination and collection of serum samples were performed at week 0 (before the onset of the training program), 3 months, and after a 6-month program of moderate aerobic training

MeSH Terms

Conditions

Diabetes Mellitus; Motor Activity

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Behavior

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical investigator

Study Record Dates

• First Submitted: January 12, 2024
• First Posted: February 7, 2024
• Study Start: February 20, 2014
• Primary Completion: August 30, 2014
• Study Completion: October 1, 2014
• Last Updated: February 7, 2024

Record last verified: 2024-01