NCT06244420

Brief Summary

The purpose of the study is to assess whether there is a correlation between imaging and histology with prognosis in patients with soft tissue and bone MC from the archives of the Rizzoli Orthopaedic Institute all the patients with a histological diagnosis of soft tissue or bone malignant myoepithelioma treated from 1998 to 2021

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
33

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 10, 2024

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

January 29, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

February 6, 2024

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2024

Completed
Last Updated

April 1, 2025

Status Verified

March 1, 2025

Enrollment Period

12 months

First QC Date

January 29, 2024

Last Update Submit

March 26, 2025

Conditions

Myoepithelioma

Outcome Measures

Primary Outcomes (1)

  • Correlation

    correlation between imaging and histology with prognosis in patients with soft tissue and bone MC.

    At baseline (Day 0)

Study Arms (1)

Patients

patients with a histological diagnosis of soft tissue or bone malignant myoepithelioma treated from 1998 to 2021.

Other: Clinical data review

Interventions

Clinical data reviewOTHER

review the medical records, radiological imaging, and histological data of these patients

Patients

Eligibility Criteria

Age2 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients with soft tissue and bone MC

You may qualify if:

  • Male and female patients treated at Rizzoli Orthopaedic Institute between 01 Jan 1998 and 31 Dec 2021
  • Age ≥ 2 years old
  • Diagnosis of soft tissue or bone malignant myoepithelioma (MC-SB)
  • Patients with available clinical and imaging data

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

IRCCS Itituto Ortopedico Rizzoli

Bologna, BO, 40136, Italy

Location

Related Publications (2)

  • Xu B, Katabi N. Myoepithelial Carcinoma. Surg Pathol Clin. 2021 Mar;14(1):67-73. doi: 10.1016/j.path.2020.09.008. Epub 2021 Jan 5.

    PMID: 33526224RESULT

  • Thway K, Fisher C. Myoepithelial tumor of soft tissue: histology and genetics of an evolving entity. Adv Anat Pathol. 2014 Nov;21(6):411-9. doi: 10.1097/PAP.0000000000000039.

    PMID: 25299310RESULT

MeSH Terms

Conditions

Myoepithelioma

Condition Hierarchy (Ancestors)

Neoplasms, Complex and MixedNeoplasms by Histologic TypeNeoplasms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 29, 2024

First Posted

February 6, 2024

Study Start

January 10, 2024

Primary Completion

December 31, 2024

Study Completion

December 31, 2024

Last Updated

April 1, 2025

Record last verified: 2025-03

Data Sharing

IPD Sharing
Will not share

Locations

IT(1)