Effect of High Versus Low-level Laser Therapy in Patients of Lumber Radiculopathy

NCT06240845 | Completed

• 1 other identifier: REC/RCR&AHS/23/0239
• Study Type: interventional
• Target: 38
• Locations: 1 country
• Sites: 2

Brief Summary

To Compare the effects of high-level laser therapy (HLLT) and low-level laser therapy (LLLT) on pain in patients with lumbar radiculopathy.

Conditions

Lumbar Radiculopathy

Keywords

HLLT, Laser therapy , LLLT, Lumber radiculopathy, Sciatica

Outcome Measures

Primary Outcomes (4)

• Pain Level

  Visual Analogue scale

  6 weeks

• Rang of motion

  Straight Leg Raise

  6 weeks

• Level of Disability

  Oswestry Disability Index (ODI)

  6 weeks

• To measure Quality of Life

  Health Questionnaire (EQ-5D-5L)

  6 weeks

Study Arms (2)

High Level Laser Therapy

EXPERIMENTAL

This group received High-level laser therapy along with conventional physiotherapy treatment 3 times per week for 6 weeks.

Other: High-level laser therapy

Low Level Laser Therapy

EXPERIMENTAL

This group received Low-level laser therapy along with conventional physiotherapy treatment 3 times per week for 6 weeks.

Other: Low-level laser therapy

Interventions

High-level laser therapy OTHER

This group received High-level laser therapy along with conventional physiotherapy treatment 3 times per week for 6 weeks.

High Level Laser Therapy

Low-level laser therapy OTHER

This group received Low-level laser therapy along with conventional physiotherapy treatment 3 times per week for 6 weeks.

Low Level Laser Therapy

Eligibility Criteria

• Age: 40 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients of both genders male and female will be included.
• Patients aged 40-65 years will be included.
• Patients with a diagnosis of lumbar radiculopathy confirmed by clinical evaluation by a physician or physiotherapist.
• Patients with a history of radicular leg pain and/or numbness or tingling sensation in the leg.
• a positive score on the Straight Leg Raise (pain between 35 degrees and 75 degrees), pain limiting functional ability, and scores at least 3/10 on the VAS, restricted lumbar range of motion - 25% flexion, 20% extension.
• Patients who have not received any form of treatment for lumbar radiculopathy within the past 3 months

You may not qualify if:

• Patients with a history of spinal surgery in the last 2 years or spinal deformity.
• Patients with a history of fracture or dislocation of the lumbar spine.
• Patients with a diagnosis of any other neurological disorder or neuropathy.
• Patients who are pregnant or breastfeeding.
• Patients with any other medical condition that may interfere i.e. inflammatory rheumatic disease, cardiac pacemaker, continuing that may interfere with the study outcomes or put them at risk with the study outcomes or put them at risk.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (2)

Faiq Medical Complex

Faisalābad, Punjab Province, 54000, Pakistan

Location

Independent University Hospital

Faisalābad, Punjab Province, 54000, Pakistan

Location

Related Publications (9)

• Kolu E, Buyukavci R, Akturk S, Eren F, Ersoy Y. Comparison of high-intensity laser therapy and combination of transcutaneous nerve stimulation and ultrasound treatment in patients with chronic lumbar radiculopathy: A randomized single-blind study. Pak J Med Sci. 2018 May-Jun;34(3):530-534. doi: 10.12669/pjms.343.14345.

  PMID: 30034410 BACKGROUND

• Ince S, Eyvaz N, Dundar U, Toktas H, Yesil H, Eroglu S, Adar S. Clinical Efficiency of High-Intensity Laser Therapy in Patients With Cervical Radiculopathy: A 12-Week Follow-up, Randomized, Placebo-Controlled Trial. Am J Phys Med Rehabil. 2024 Jan 1;103(1):3-12. doi: 10.1097/PHM.0000000000002275. Epub 2023 May 1.

  PMID: 37204965 BACKGROUND

• Konstantinovic LM, Cutovic MR, Milovanovic AN, Jovic SJ, Dragin AS, Letic MDj, Miler VM. Low-level laser therapy for acute neck pain with radiculopathy: a double-blind placebo-controlled randomized study. Pain Med. 2010 Aug;11(8):1169-78. doi: 10.1111/j.1526-4637.2010.00907.x.

  PMID: 20704667 BACKGROUND

• Ahmed I, Bandpei MAM, Gilani SA, Ahmad A, Zaidi F. Effectiveness of Low-Level Laser Therapy in Patients with Discogenic Lumbar Radiculopathy: A Double-Blind Randomized Controlled Trial. J Healthc Eng. 2022 Feb 27;2022:6437523. doi: 10.1155/2022/6437523. eCollection 2022.

  PMID: 35265302 BACKGROUND

• Ahmed I, Mohseni Bandpei MA, Gilani SA, Ahmad A, Zaidi F. Correlation Analysis Between Pain Intensity, Functional Disability and Range of Motion Using Low-Level Laser Therapy in Patients With Discogenic Lumbar Radiculopathy: A Cross-sectional Study. J Lasers Med Sci. 2022 Jun 6;13:e26. doi: 10.34172/jlms.2022.26. eCollection 2022.

  PMID: 36743144 BACKGROUND

• Danazumi MS, Bello B, Yakasai AM, Kaka B. Two manual therapy techniques for management of lumbar radiculopathy: a randomized clinical trial. J Osteopath Med. 2021 Feb 26;121(4):391-400. doi: 10.1515/jom-2020-0261.

  PMID: 33705612 BACKGROUND

• Rogerson A, Aidlen J, Jenis LG. Persistent radiculopathy after surgical treatment for lumbar disc herniation: causes and treatment options. Int Orthop. 2019 Apr;43(4):969-973. doi: 10.1007/s00264-018-4246-7. Epub 2018 Nov 29.

  PMID: 30498910 BACKGROUND

• Kostadinovic S, Milovanovic N, Jovanovic J, Tomasevic-Todorovic S. Efficacy of the lumbar stabilization and thoracic mobilization exercise program on pain intensity and functional disability reduction in chronic low back pain patients with lumbar radiculopathy: A randomized controlled trial. J Back Musculoskelet Rehabil. 2020;33(6):897-907. doi: 10.3233/BMR-201843.

  PMID: 32675390 BACKGROUND

• Ghasabmahaleh SH, Rezasoltani Z, Dadarkhah A, Hamidipanah S, Mofrad RK, Najafi S. Spinal Manipulation for Subacute and Chronic Lumbar Radiculopathy: A Randomized Controlled Trial. Am J Med. 2021 Jan;134(1):135-141. doi: 10.1016/j.amjmed.2020.08.005. Epub 2020 Sep 13.

  PMID: 32931763 BACKGROUND

MeSH Terms

Conditions

Radiculopathy; Sciatica

Interventions

Low-Level Light Therapy

Condition Hierarchy (Ancestors)

Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Sciatic Neuropathy; Mononeuropathies; Neuralgia; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Laser Therapy; Therapeutics; Phototherapy

Study Officials

• Binash Afzal, PHD*

  Riphah international university lahore campus

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 28, 2024
• First Posted: February 5, 2024
• Study Start: August 1, 2023
• Primary Completion: September 30, 2023
• Study Completion: October 10, 2023
• Last Updated: February 5, 2024

Record last verified: 2024-01

Data Sharing

• IPD Sharing: Will not share

Locations

PA (2)