Association of Acne Vulgaris With Oral Hygiene and Gingivitis

NCT06237387 | Not Yet Recruiting

• 1 other identifier: EUDF-OKUMUS-003
• Study Type: observational
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

The goal of this observational study is to learn about in the relationship between acne vulgaris and oral hygiene and gingivitis. The main questions it aims to answer are:

• Is there a relationship between the severity of acne vulgaris lesions and the severity of plaque-related gingivitis?
• Could oral hygiene or the severity of plaque-related gingivitis have an impact on the treatment of acne lesions? Participants will;
• First be examined at the dermatology clinic.
• Then be examined at the periodontology clinic.
• Participants with severe acne vulgaris lesions will be examined a second time at the dermatology clinic. (1.5 months after the first examination)
• Regularly use the antibiotic containing 100 mg doxycycline prescribed in the dermatology clinic for acne treatment. (Patients deemed suitable by the dermatologist)

Conditions

Acne Vulgaris; Gingivitis; Dental Plaque; Oral Hygiene; Puberty

Outcome Measures

Primary Outcomes (3)

• The relationship between acne vulgaris and the severity of gingivitis depending on the amount of plaque

  Data from three groups will be presented as the correlation between the Gingival Index score and the Plaque Index score. The relationship between the severity of gingival inflammation depending on the amount of plaque and acne lesions will be evaluated.

  Baseline

• The relationship between acne vulgaris and oral hygiene

  Describes the relationship between plaque index data obtained during periodontal examination of patients and acne lesions. According to the plaque index system, a score of "0" indicates the absence of plaque. A score of "1" refers to the amount of plaque that is not visible to the eye but detected by the periodontal probe. A score of "2" refers to the amount of plaque detectable visually. The highest score, "3", indicates excessive plaque accumulation.

  Baseline

• Relationship between acne vulgaris and gingival index

  To compare gingival index values obtained during periodontal examination with acne vulgaris, regardless of plaque index values. According to the gingival index system, a score of "0" indicates completely healthy gums. A score of "1" indicates mild erythema and no bleeding on probing. A score of "2" indicates a small amount of bleeding on probing. The highest score, "3", indicates spontaneous or excessive gingival bleeding.

  Baseline

Secondary Outcomes (3)

• The relationship between response to medical treatment and severity of gingivitis depending on the amount of plaque

  At the end of 1.5 months from the beginning

• The relationship between response to medical treatment and oral hygiene

  At the end of 1.5 months from the beginning

• The relationship between response to medical treatment and gingival index

  At the end of 1.5 months from the beginning

Study Arms (3)

Group A

Patients with Allen-Smith acne score 0 and 2 (Mild lesions)

Other: Periodontal examination

Group B

Patients with Allen-Smith acne score 4 (Moderate lesions)

Other: Periodontal examination

Group C

Patients with Allen-Smith acne score 6 and 8 (Severe lesions)

Other: Periodontal examination

Interventions

Periodontal examination OTHER

Determining the patient's oral hygiene status and the severity of gingivitis. For this purpose, the non-invasive Löe-Silness plaque and gingival index system will be used.

Group A; Group B; Group C

Eligibility Criteria

• Age: 13 Years - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Participants in puberty between the ages of 13-18.

You may qualify if:

• Being systemically healthy
• Not using any medication regularly
• Not having received acne treatment before
• Not having a known allergy to Doxycycline/Tetracycline antibiotics
• Not having received periodontal disease treatment in the last 6 months
• Not having taken antibiotics or anti-inflammatory drugs in the last month
• Not having used antiseptic mouthwash in the last month
• Being between the ages of 13-18
• No radiographic bone loss or clinical attachment loss
• Absence of any diagnosed psychiatric disease

You may not qualify if:

• Smoking
• Using antibiotics and anti-inflammatory drugs
• Having significant psychological problems
• Mouth breathing

Sponsors & Collaborators

• Erzincan University: lead

MeSH Terms

Conditions

Acne Vulgaris; Gingivitis; Dental Plaque

Condition Hierarchy (Ancestors)

Acneiform Eruptions; Skin Diseases; Skin and Connective Tissue Diseases; Sebaceous Gland Diseases; Infections; Gingival Diseases; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases; Dental Deposits; Tooth Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: January 24, 2024
• First Posted: February 1, 2024
• Study Start: June 5, 2024
• Primary Completion: June 15, 2024
• Study Completion: July 15, 2024
• Last Updated: May 28, 2024

Record last verified: 2024-05