NCT06235619

Brief Summary

The aortic arch with a common origin of the innominate and left carotid artery (CILCA) prevalence in the general population is 13.6%. Its reputation as a benign anatomical variant has been ultimately shattered by further studies that identified the CILCA arch as a potential marker for thoracic aortic disease (TAD) The aim of this work is to report the CT anatomical characteristics of the aortic arch in subjects with or without aneurysms requiring treatment, in 5 major European cardiovascular centers.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
7mo left

Started Sep 2024

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress75%
Sep 2024Dec 2026

First Submitted

Initial submission to the registry

January 23, 2024

Completed
9 days until next milestone

First Posted

Study publicly available on registry

February 1, 2024

Completed
7 months until next milestone

Study Start

First participant enrolled

September 1, 2024

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2025

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2026

Expected
Last Updated

May 2, 2025

Status Verified

April 1, 2025

Enrollment Period

1.2 years

First QC Date

January 23, 2024

Last Update Submit

April 30, 2025

Conditions

Aortic ArchAneurysmDissection, Aortic

Keywords

Aortic archBovine archThoracic aortic disease

Outcome Measures

Primary Outcomes (1)

  • difference from baseline of aortic arch anomalies

    record of anatomical variations of the aortic arch

    30 day

Study Arms (2)

Non aneurysm patients

CT anatomical characteristics of the aortic arch in subjects without aneurysms requiring treatment.

Aneurysm patients

CT anatomical characteristics of the aortic arch in subjects withaneurysms requiring treatment.

Eligibility Criteria

Age0 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The population of the study is the general population undergoing Angio CT scan both the thoracic aorta

You may qualify if:

  • all patients with aortic arch CT scan at investigating centers

You may not qualify if:

  • none

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

IRCCS San Raffaele Hospital

Milan, Italy, 20132, Italy

RECRUITING

MeSH Terms

Conditions

AneurysmAortic Dissection

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular DiseasesDissection, Blood VesselAcute Aortic SyndromeAortic Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof.

Study Record Dates

First Submitted

January 23, 2024

First Posted

February 1, 2024

Study Start

September 1, 2024

Primary Completion

December 1, 2025

Study Completion (Estimated)

December 1, 2026

Last Updated

May 2, 2025

Record last verified: 2025-04

Locations

IT(1)