NCT06234410|Recruiting
Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation
CRAFT-CTCA
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CRAFT-CTCA
Sponsor study identifier
observational
332
1 country
2
Study Start
January 24, 2024
Actual (reported)Primary Completion
January 2032
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
January 2032
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Cardiovascular disease (for example, heart attack, stroke, heart failure) is the commonest complication of kidney failure. Kidney transplantation reduces cardiovascular risk but cardiovascular disease remains the commonest cause of death in patients following transplantation. Current strategies to assess patient's cardiovascular risk prior to kidney transplantation do not identify those at highest risk and do not improve outcomes. This study will use a heart scan known as computed tomography coronary angiography (CTCA) to see whether this scan can identify patients at highest risk of future cardiovascular disease prior to transplantation. Studies have shown it is able to do this in patients with normal kidney function. The aim of this study is to develop CTCA as an effective tool to risk stratify patients prior to kidney transplantation.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 2032
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 22, 2024
Actual (reported)January 24, 2024
Actual (reported)January 31, 2024
Actual (reported)January 2032
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
January 2032
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Number of participants who have either a myocardial infarction or cardiovascular death
The first event of myocardial infarction or cardiovascular death
From time of CTCA scan to 36- and 60-months follow-up
Number of participants who have a fatal or non-fatal myocardial infarction
From time of CTCA scan to 36- and 60-months follow-up
Number of participants who are hospitalised due to any cardiovascular event
From time of CTCA scan to 36- and 60-months follow-up
Number of participants who die (all-cause death)
From time of CTCA scan to 36- and 60-months follow-up
Number of participants who have a cardiovascular death
From time of CTCA scan to 36- and 60-months follow-up
Number of participants who suffer a clinically significant acute kidney injury following study CTCA scan
From time of CTCA scan to 28 days follow-up
Number of participants who have clinically significant abnormal non-cardiac findings on study CTCA scan
From time of CTCA scan to 12 months follow-up
Patients who have been placed on the waiting list for a kidney transplant within Scotland
Single CTCA scan prior to kidney transplantation
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Patients on the kidney transplant waitlist
Royal Infirmary of Edinburgh
Edinburgh, Lothian, EH16 4SA, United Kingdom
Queen Elizabeth Hospital
Glasgow, G51 4TF, United Kingdom
Serum and plasma (including for potential genetic analysis) will be taken from participants and stored.
Neeraj Dhaun, MBChB
University of Edinburgh
First Submitted
January 22, 2024
First Posted
January 31, 2024
Study Start
January 24, 2024
Actual (reported)Primary Completion
January 2032
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Investigating the Effects of Green Tea on Blood Viscosity
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Study Completion
January 2032
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
February 13, 2026
Record last verified: 2026-02
Following publication of the primary paper, a deidentified individual participant data set will be will be made available for data sharing purposes, subject to necessary governance approvals. Access to the deidentified dataset will be under a controlled access model.
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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