NCT06226935

Brief Summary

In conclusion, the study shows that the hospital-based group had a significantly higher screening uptake than the community-based group, reflecting that information from ophthalmologists and registered ophthalmic nurses is more effective and well-received than that from village health volunteers. The study suggests that increasing education and support for village health volunteers could enhance screening uptake. Factors influencing uptake include the age of FDRs, place of residence, education, presenting VA of probands, and treatment of probands. Utilizing this study's findings, spreading knowledge and training health officials at the district and sub-district levels could increase understanding of glaucoma and improve communication with the general public and at-risk groups, potentially increasing the response rate. Additionally, implementing a national free screening glaucoma program for at-risk populations, both in and outside hospitals, and organizing mobile screening units at the district level could be an effective prevention strategy against permanent vision loss from glaucoma.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,304

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2022

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2022

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2023

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

January 18, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

January 26, 2024

Completed
Last Updated

January 30, 2024

Status Verified

January 1, 2024

Enrollment Period

11 months

First QC Date

January 18, 2024

Last Update Submit

January 26, 2024

Conditions

Keywords

Glaucoma ScreeningFirst-Degree RelativesCommunity-Based ApproachHospital-Based ApproachFamilial Risk Factors

Outcome Measures

Primary Outcomes (1)

  • This study aimed to evaluate the differences in glaucoma screening uptake among FDRs in community and hospital-based settings

    All patients with POAG who had a treatment history in OPD of Prapokklao Hospital, Chanthaburi Province, were identified from EMR database with ICD-10 "H40.1". These probands were then divided into two non-randomized groups: The first group, hospital-based, these patients received information from ophthalmologists and registered ophthalmic nurses, along with a brochure .Subsequently, these patients were asked to invite their FDRs - aged 40 years and above - to participate in screening. The second group, community-based, involved randomly selecting districts in Chanthaburi Province for screening, including Muang and Laem Sing districts. After excluded the patients already participating in the hospital-based group from the EMR database, 682 probands remained in the second group. In this group, village health volunteers trained in glaucoma knowledge by ophthalmologists distributed brochures and educated patients and FDRs.

    Jan 1,2022-May 31,2023

Secondary Outcomes (1)

  • This study investigated the determinants influencing participation in glaucoma screening programs and the prevalence of glaucoma in FDRs.

    Jan 1,2022-May 31,2023

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

These probands were then divided into two non-randomized groups: The first group, hospital-based, included all probands receiving treatment in the ophthalmology outpatient department from 1 dec 2022 to 28 feb 2023. These patients received information about glaucoma from ophthalmologists and registered ophthalmic nurses, along with a brochure. These patients were asked to invite FDRs-parents, siblings, and offspring aged 40 years and above - to participate screening. The second group, community-based, involved randomly selecting districts in Chanthaburi In this group, village health volunteers trained in glaucoma knowledge by ophthalmologists distributed brochures and educated patients and FDRs, similar to the hospital-based group. These FDRs were then invited to participate in the glaucoma screening program one month later, with ophthalmologists at health stations near homes in Muang district and Laem Sing Hospital between 1 mar 2023 to 31 may 2023.

You may qualify if:

  • All patients with POAG who had a treatment history in the ophthalmology outpatient department of Prapokklao Hospital, Chanthaburi Province, were identified from the Electronic Medical Record (EMR) database with the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10) " Primary open angle glaucoma H40.1" between 1 january 2022 to 31 october 2022. A total of 1304 patients were included in this study.

You may not qualify if:

  • Excluding those with closed-angle glaucoma and secondary glaucoma due to other conditions such as accidents, post-surgical complications, uveitis, or congenital.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Phrapokklao Hospital

Chanthaburi, 22000, Thailand

Location

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Target Duration
6 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
ophthalmology department

Study Record Dates

First Submitted

January 18, 2024

First Posted

January 26, 2024

Study Start

January 1, 2022

Primary Completion

December 1, 2022

Study Completion

May 31, 2023

Last Updated

January 30, 2024

Record last verified: 2024-01

Locations