Probiotic Supplementation on Sport Performance and Gut Damage in Females

NCT06220110 | Completed

• 1 other identifier: Lact.Bas.F
• Study Type: interventional
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

This study will be performed with the aim to evaluate the effects of probiotic supplementation on sport performance and gut damage. Participants will be divided into two groups, placebo and experimental group. With the purpose to assess the effects of probiotics on the gut damage, a strenuous exercise session will be performed, and then blood samples will be taken to observe the variation of the selected intestinal damage marker. 24 hours after this strenuous session, performance tests will be performed. After the 4 weeks of supplementation, the same procedure will be followed to evaluate the effect of probiotics.

Conditions

Sport Performance; Gut Damage

Keywords

Probiotic; Gut damage; Sport performance; Females

Outcome Measures

Primary Outcomes (4)

• Intestinal-fatty acid-binding protein

  Gut damage marker

  0-10 minutes after strenuous exercise blood samples will be extracted

• Counter movement jump test

  Jumping test

  24 hours after strenuous training session. First test to be performed

• Running Based Anaerobic Sprint Test

  Running test

  24 hours after strenuous training session. Second test to be performed

• YO YO Intermittent Recovery Level test 1

  aerobic test

  24 hours after strenuous training session. Third test to be performed

Study Arms (2)

Experimental group

EXPERIMENTAL

Probiotic intake containing 10 billions of Colony Forming Units of Lactobacillus plantarum (1 capsule per day)

Dietary Supplement: Probiotic

Placebo group

PLACEBO COMPARATOR

Placebo intake. Placebo capsules will contain dextrose (1 capsule per day)

Dietary Supplement: Placebo

Interventions

Probiotic DIETARY_SUPPLEMENT

Probiotic capsules will be composed of 10 billion CFU of Lactobacillus plantarum.

Experimental group

Placebo DIETARY_SUPPLEMENT

Capsules containing dextrose (1 capsule per day)

Placebo group

Eligibility Criteria

• Age: 18 Years+
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy
• No injuries
• year of CrossFit practicing experience

You may not qualify if:

• Drug, alcohol, cigarettes, probiotic intake
• Injuries

Sponsors & Collaborators

• University of the Basque Country (UPV/EHU): lead

Study Sites (1)

CrossFit Bikain

Vitoria-Gasteiz, Alava, 01015, Spain

Location

MeSH Terms

Interventions

Probiotics

Intervention Hierarchy (Ancestors)

Dietary Supplements; Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Asier Santibañez, MsC

  University of the Basque Country (UPV/EHU)

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: January 12, 2024
• First Posted: January 23, 2024
• Study Start: October 15, 2023
• Primary Completion: November 15, 2023
• Study Completion: December 15, 2023
• Last Updated: January 24, 2024

Record last verified: 2024-01

Locations

ES (1)