Assessment of the Impact of Early Treatment for Anorexia Nervosa in a Day Hospital on Food Symptomatology, the Outcome of Young Patients, and the Family Experience

NCT06218472 | Recruiting

• 2 other identifiers: APHP2315942023-A02047-38
• Study Type: observational
• Target: 164
• Locations: 1 country
• Sites: 1

Brief Summary

During the management of chronic illnesses, the day hospital (DH) serves as a brief and effective alternative to traditional hospitalization, offering access to multidisciplinary care. Indeed, patients can benefit from a range of therapeutic tools provided by a multidisciplinary care team while remaining in their living environment. Numerous structures exist for the management of eating disorders, but primarily for severe cases, often following hospitalization, before transitioning to outpatient care. There is no alternative for the initial management of these patients. The DH for the evaluation and early intervention in recent forms of anorexia nervosa at Maison de Solenn serves as a rapid entry point to specialized care. It allows for a thorough assessment and sustained management of eating disorders. Our hypothesis is that a multidisciplinary, intensive, and early intervention for patients with anorexia nervosa and their families in a day hospital would improve the short, medium, and long-term prognosis of the disease compared to conventional multidisciplinary outpatient care. It would also enhance the family's experience of this pathology and their coping skills.

Conditions

Anorexia Nervosa

Keywords

Anorexia nervosa; Family-based treatment; Day hospital; Early intervention; Parental experience

Outcome Measures

Primary Outcomes (1)

• Occurrence of one or more clinical events

  Occurrence of one or more clinical events indicative of the progression of this disease (hospitalization, emergency room visits, major decompensation) at 1 year. Evaluate the impact of early intervention in DH on the clinical progression of the disease compared to the usual outpatient care.

  1 year after inclusion

Secondary Outcomes (6)

• Occurrence of one or more clinical events

  5 years after inclusion

• Conduct semi-structured qualitative interviews

  After DH termination = 12 weeks after inclusion

• Satisfaction questionnaire CSQ-8 (Consumer satisfaction questionnaire)

  After DH termination = 12 weeks after inclusion

• Clinical characteristics collection

  Inclusion

• Socio-demographic characteristics collection

  Inclusion

Study Arms (3)

Day hospital patient

Acceptance of the DH program (DH group): scheduling of 10 to 12 sessions over 12 weeks during a program session, followed by a reassessment at the end of the program. Outpatient follow-up thereafter.

Other: Day Hospital Treatment

Outpatient

Refusal or inability to participate in the DH program: multidisciplinary follow-up "as usual" within the service (outpatient group).

Other: Multidisciplinary follow-up "as usual" within the service

Parents

Other: Conduct semi-structured qualitative interviews

Interventions

Day Hospital Treatment OTHER

Scheduling of 12 half-day sessions per week, alternating between sessions with only the patients or involving the entire family. Close medical monitoring and multidisciplinary interventions during sessions (pediatrician, psychiatrist, dietitian, recovered former patients...).

Also known as: Family based treatment

Day hospital patient

Multidisciplinary follow-up "as usual" within the service OTHER

Multidisciplinary follow-up "as usual" within the service

Outpatient

Conduct semi-structured qualitative interviews OTHER

Conduct semi-structured qualitative interviews

Parents

Eligibility Criteria

• Age: 12 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This study will include patients of any gender aged 12 to 18 years and their parents, seen in consultation for anorexia nervosa at the pedopsychiatric unit of the Cochin Hospital, Paris, France.

You may qualify if:

• Adolescents in the age range of 12-18 years and their parents,
• First-time consultation at the MDA for anorexia nervosa (according to DSM-5) evolving for less than 12 months,
• Adolescents with clinical characteristics suitable for DH care.

You may not qualify if:

• Parents and/or children who do not speak French or cannot read or write,
• Patients who have been followed by an eating disorder specialist in the past 12 months (at the MDA or elsewhere) or previously hospitalized for anorexia nervosa,
• Patients who have undergone family therapy in the past,
• Patients with BMI less than 13 kg/m2 for those under 14 years old, or less than 14 kg/m2 for those over 14 years old at the initial assessment,
• Patients with a major psychiatric comorbidity or a metabolic condition interfering with eating or its regulation,
• Patients and families in a crisis situation requiring immediate hospitalization.

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris: lead
• URC-CIC Paris Descartes Necker Cochin: collaborator

Study Sites (1)

Maison de Solenn Maison des Adolescents, Cochin Hospital

Paris, IDF, 75014, France

RECRUITING

MeSH Terms

Conditions

Anorexia Nervosa

Condition Hierarchy (Ancestors)

Feeding and Eating Disorders; Mental Disorders

Central Study Contacts

Corinne BLANCHET, MD, PhD

CONTACT

00 33 1 58 41 24 24; corinne.blanchet@aphp.fr

Marie BENHAMMANI-GODARD

CONTACT

00 33 1 58 41 11 90; marie.godard@aphp.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 8, 2024
• First Posted: January 23, 2024
• Study Start: February 19, 2024
• Primary Completion (Estimated): February 1, 2028
• Study Completion (Estimated): April 1, 2032
• Last Updated: January 29, 2026

Record last verified: 2026-01

Locations

FR (1)