Brief Summary

This clinical trial studies how well a remotely delivered home-based exercise program for strength training works to positively impact endometrial cancer (EC) survivorship for patients with decreased cancer survivorship access. Cancer survivors in rural areas face barriers to supportive care, including geographic and environmental barriers to exercise and technology. Rural areas in the Midwest are underserved in terms of cancer care thus, it is essential to develop and test interventions that are scalable and can reach many individuals including those living in rural areas. Remotely-delivered exercise intervention approach allows for cancer survivors who may live far away from their primary treatment center to engage in supportive therapy via exercise interventions delivered in a sustainable context. In addition, historically black, hispanic and native endometrial cancer survivors have shorter survival and less access to survivorship care, so alternative models for healthcare delivery are needed in this underserved group. Information gained from this research may help determine whether utilizing a remotely delivered exercise program can positively impact EC survivorship for patients with decreased cancer survivorship access.

Trial Health

Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date

Enrollment

participants targeted

Target at P50-P75 for not_applicable

Timeline

Completed

Started Mar 2024

Typical duration for not_applicable

Geographic Reach

1 country

1 active site

Status

active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

2 years study duration

First Submitted

Initial submission to the registry

January 10, 2024

Completed

9 days until next milestone

First Posted

Study publicly available on registry

January 19, 2024

Completed

2 months until next milestone

Study Start

First participant enrolled

March 22, 2024

Completed

2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2026

Completed

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2026

Completed

Last Updated

January 9, 2026

Status Verified

January 1, 2026

Enrollment Period

2 years

First QC Date

January 10, 2024

Last Update Submit

January 7, 2026

Conditions

FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma Stage IA Uterine Corpus Cancer AJCC v8 Stage IB Uterine Corpus Cancer AJCC v8

Outcome Measures

Primary Outcomes (3)

Retention of participants
Assessed by the number of patients who complete 75% or more of the twice weekly exercise program.
Up to 6 months
Satisfaction with program - self-reported
Assessed by a simple participant satisfaction survey after completion of the 10-week exercise intervention. Qualitative interviews will be performed at the completion of the program regardless of level of participation to assess facilitators, barriers, and motivators to participation.
10 weeks
Feasibility of intervention
Technological questions and problems that arise during the exercise intervention will be recorded to assess the ability to fully perform telehealth exercise interventions in a rural cancer population
Up to 6 months

Secondary Outcomes (1)

Change in physical function
Baseline; 10 weeks (end of exercise intervention); 6 months

Study Arms (1)

Supportive Care (home-based exercise program)

EXPERIMENTAL

Participants participate in a home-based exercise program with an exercise prescription that will include resistance band and body weight exercises targeting the 5 major large muscle groups along with 3 booklets about exercise and exercise training and attend weekly exercise coaching sessions to report on exercise adherence and to progress exercise over 10 weeks on study.

Other: Exercise CounselingOther: Exercise InterventionOther: Health Promotion and EducationOther: InterviewOther: Physical Performance TestingOther: Questionnaire AdministrationOther: Telemedicine