Biomarkers in Prediction of AMI
BIPAMI
Biomarkers In Prediction of Acute Mesenteric Ischaemia: a Prospective Multicentre Study (BIPAMI Study)
1 other identifier
interventional
250
2 countries
2
Brief Summary
Current study will be undertaken to identify combinations of biomarkers that can reliably identify acute mesenteric ischaemia (AMI) and distinguish between non-transmural and transmural ischaemia. Different combinations of biomarkers for different sub-types and severity of AMI, and different time points of measurement after onset of symptoms.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Oct 2024
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 4, 2024
CompletedFirst Posted
Study publicly available on registry
January 19, 2024
CompletedStudy Start
First participant enrolled
October 14, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2025
CompletedDecember 3, 2024
November 1, 2024
11 months
January 4, 2024
November 27, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Rate of correctly predicted cases of acute mesenteric ischaemia
Rate of correctly predicted cases of Acute mesenteric ischaemia using different biomarkers
10 months
Study Arms (1)
Patient with suspicion of acute mesenteric ischaemia
OTHERBolld samples is the only intervention. All patients with suspicion of AMI will be included and blood samples collected
Interventions
Sequential blood samples for diagnostic tests is the only intervention in thei study
Eligibility Criteria
You may qualify if:
- Age 18 years or older
- Initial decision in favour of further diagnostics of mesenteric ischaemia
You may not qualify if:
- Age \<18 years
- Consent declined by patient or next of kin (delayed consent)
- Chronic mesenteric ischaemia without an acute event
- Immediate decision for withdrawal of further diagnostics and active treatment
- Referral from another hospital with already established diagnosis of AMI
- AMI diagnosed at surgery without previously having been considered
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Tartu University Hospital
Tartu, 50406, Estonia
Lucerne Cantonal Hospital
Lucerne, 6000, Switzerland
Related Publications (1)
Tamme K, Acosta S, Biloslavo A, Bjorck M, Casian D, Damaskos D, Forbes A, Kase K, Kisand K, Lakbar I, Mihnovits V, Murruste M, Mandul M, Nuzzo A, Padar M, Starkopf J, Visconti D, Reintam Blaser A. Biomarkers In Prediction of Acute Mesenteric Ischaemia: a prospective multicentre study (BIPAMI study): a study protocol. BMC Surg. 2024 Jul 3;24(1):201. doi: 10.1186/s12893-024-02491-3.
PMID: 38961419DERIVED
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
January 4, 2024
First Posted
January 19, 2024
Study Start
October 14, 2024
Primary Completion
September 1, 2025
Study Completion
December 1, 2025
Last Updated
December 3, 2024
Record last verified: 2024-11
Data Sharing
- IPD Sharing
- Will not share