Effect of Neuromuscular Electrical Stimulation Applied to the Lumbar Multifidus Muscle on Sit to Stand Kinematics in Individuals With Low Back Pain

NCT06212011 | Completed

• 1 other identifier: 204574
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this randomized controlled trial, is to investigate the effect of functional NMES and conventional NMES applied to the lumbar multifidus muscle on body kinematic and kinetic values during the sit-to-stand in individuals with non-specific low back pain. Our study will include 24 participants between the ages of 18-65. Which physiotherapy intervention will be applied to the participants will be determined by the block randomization method, using a table of random numbers. After randomization; NMES to the participants' lumbar multifidus muscle during physiotherapy intervention will be applied in two groups; In the first group, NMES will be applied with the conventional technique during prone position and in the second group, NMES will be applied with the functional technique during the sit-to-stand activity. Evaluations will be made twice for each participant- before and after the intervention. During the evaluation, data regarding the change in body kinetics and kinematics of individuals during the sit-to-stand activity will be recorded with a Vicon camera system. For secondary outcome measures, a visual analog scale will be used to evaluate pain, the Roland Morris Disability Questionnaire and the Oswestry Disability Index will be used to evaluate functional status, and the Tampa Kinesiophobia Scale will be used to evaluate fear-avoidance behavior.

Conditions

Low Back Pain

Keywords

low back pain; electric stimulation; sit to stand; kinetic; kinematic

Outcome Measures

Primary Outcomes (2)

• Changes in kinematics of the Lumbar Spine and Hip During sit-to-stand activity

  With kinematic analysis, the mean, minimum and maximum range of motion of the lumbar spine and hip joint during the sit-to-stand activity will be evaluated and recorded in degrees using the vicon motion capture system (Vicon, 6xVantage 5 Cameras 5MP@420FPS, 2xVue Video Cameras).

  Baseline and first week after 8-week intervention

• Changes in ground reaction force during sit-to-stand activity

  Ground reaction force will be evaluated using force plates (2xAMTI force plates).

  Baseline and first week after 8-week intervention

Secondary Outcomes (7)

• Hip and Lumbar spine range of motion

  Baseline and first week after 8-week intervention

• Shortness of the hip flexor, knee flexor and plantar flexor muscles

  Baseline and first week after 8-week intervention

• Beighton test

  Baseline and first week after 8-week intervention

• Visual analogue scale

  Baseline and first week after 8-week intervention

• Oswestry Disability Index

  Baseline and first week after 8-week intervention

Study Arms (2)

Functional Neuromuscular Electrical Stimulation Group

EXPERIMENTAL

Functional NMES involves stimulating the lumbar multifidus muscle while the individual performs a sit-to-stand activity.

Other: Functional Neuromuscular Electrical Stimulation

Conventional Neuromuscular Electrical Stimulation Group

EXPERIMENTAL

Conventional NMES intervention involves only stimulating the lumbar multifidus muscle while the individual is in the prone position, and the individual will not reveal any voluntary contraction during stimulation.

Other: Conventional Neuromuscular Electrical Stimulation

Interventions

Functional Neuromuscular Electrical Stimulation OTHER

The functional NMES technique involves the application of electrical stimulation during functional activity. In our study, in the functional neuromuscular electrical simulation group, neuromuscular electrical stimulation will be applied to the lumbar multifidus muscle while individuals perform the activity of standing up from sitting.

Functional Neuromuscular Electrical Stimulation Group

Conventional Neuromuscular Electrical Stimulation OTHER

The conventional neuromuscular electrical simulation technique, electrical stimulation is applied without the individual performing voluntary contractions. In our study, conventional NMES will be applied to the lumbar multifidus muscle with the individual lying in the prone position and the individual will not elicit any voluntary contractions during the simulation.

Conventional Neuromuscular Electrical Stimulation Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• History of chronic low back pain (12 weeks\<)
• Pain in the lumbar and/or hip area (VAS\>3)
• Volunteering to participate in the study

You may not qualify if:

• History of neurological, metabolic, cardiovascular disease
• Having had spinal surgery, specific lumbar pathology, scoliosis, pregnancy, history of systemic or degenerative disease
• Musculoskeletal system pathology in the last year
• Body mass index being over 30 kg/m2
• Continuing any exercise program

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe University

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Low Back Pain

Condition Hierarchy (Ancestors)

Back Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 24, 2023
• First Posted: January 18, 2024
• Study Start: May 1, 2024
• Primary Completion: June 10, 2025
• Study Completion: June 15, 2025
• Last Updated: July 2, 2025

Record last verified: 2025-04

Locations

TU (1)