Association With Low Compliance Bladder in Women With LUTS

NCT06210477 | Completed

• 1 other identifier: 202303086RINC
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Hypothesis / aims of study The clinical and urodynamic features on the severity of low compliance bladder in neurologically intact women with lower urinary tract symptoms are indeterminate. Thus, this study aimed to elucidate the above association. Study design, materials and methods Between January 1996 and December 2021, the medical records of all consecutive women who underwent urodynamic studies for their lower urinary tract symptoms were reviewed to elucidate the clinical significance of low bladder compliance.

Conditions

Urinary Bladder, Overactive; Urinary Bladder Neck Obstruction; Pelvic Organ Prolapse; Urinary Incontinence

Outcome Measures

Primary Outcomes (1)

• Bladder capacity (mL)

  To compare the bladder capacity (mL) between the groups with and without low bladder compliance. The bladder capacity will be derived from the filling cystometry of urodynamic studies.

  1996/1/1~2021/12/31

Secondary Outcomes (1)

• Persistence rates of treatment (%)

  1996/1/1~2021/12/31

Study Arms (1)

Low compliance

Low urinary tract symptoms with low bladder compliance

Drug: medical treatment for lower urinary tract symptoms

Interventions

medical treatment for lower urinary tract symptoms DRUG

The clinical and urodynamic features on the severity of low compliance bladder in neurologically intact women with lower urinary tract symptoms are indeterminate. Thus, this study aimed to elucidate the above association.

Also known as: antimuscarinics

Low compliance

Eligibility Criteria

• Age: 18 Years+
• Gender Eligibility Details: women who underwent urodynamic studies
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Women with lower urinary tract symptoms

You may qualify if:

• Urodynamic finding with low bladder compliance

You may not qualify if:

• Nil.

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

Department of Obstetrics and Gynecology, National Taiwan University Hospital

Taipei, 100, Taiwan

Location

MeSH Terms

Conditions

Urinary Bladder, Overactive; Urinary Bladder Neck Obstruction; Pelvic Organ Prolapse; Urinary Incontinence

Interventions

Muscarinic Antagonists

Condition Hierarchy (Ancestors)

Urinary Bladder Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Lower Urinary Tract Symptoms; Urological Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Urethral Obstruction; Urethral Diseases; Prolapse; Pathological Conditions, Anatomical; Urination Disorders

Intervention Hierarchy (Ancestors)

Cholinergic Antagonists; Cholinergic Agents; Neurotransmitter Agents; Molecular Mechanisms of Pharmacological Action; Pharmacologic Actions; Chemical Actions and Uses; Physiological Effects of Drugs

Study Officials

• Ho-Hsiung Lin, MD, PhD

  Department of Obstetrics and Gynecology, National Taiwan University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 22, 2023
• First Posted: January 18, 2024
• Study Start: January 31, 2024
• Primary Completion: December 31, 2024
• Study Completion: December 31, 2024
• Last Updated: February 19, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)