NCT06208319

Brief Summary

Project aiming to develop an algorithm to help the interpretation of colposcopy images, then to evaluate the effectiveness of this algorithm by using it on new cases and comparing the results obtained to the impression of expert clinicians

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2024

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 4, 2024

Completed
13 days until next milestone

First Posted

Study publicly available on registry

January 17, 2024

Completed
1 month until next milestone

Study Start

First participant enrolled

March 1, 2024

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2024

Completed
Last Updated

February 1, 2024

Status Verified

January 1, 2024

Enrollment Period

8 months

First QC Date

January 4, 2024

Last Update Submit

January 31, 2024

Conditions

Keywords

Artificial IntelligenceColposcopyMachine LearningAlgorithmPapillomavirusCervical Cancer

Outcome Measures

Primary Outcomes (1)

  • Development of an algorithm to help interpret colposcopy images

    Creation of an imaging database with correlation to clinical and histological data, using data from care at the Pitié-Salpêtrière Hospital. A hundred cases will be selected for the study from the hundreds available in the department. Annotation of colposcopy photos according to the recommendations of the French Society of Colposcopy and Cervico Vaginal Pathology (SFCPCV), then correlation with histological data. Development of an algorithm for recognizing and analyzing colposcopy photos, with the help of a computer science student, using the analyzed data.

    4 month after inclusion

Secondary Outcomes (1)

  • Evaluate the effectiveness of this algorithm

    4 month after inclusion

Interventions

data collection from the patient's medical record. The data will be that of routine care, with no procedures added by the research.

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

\- Adult patients who underwent colposcopy with directed biopsies at La Pitié-Salpêtrière between September 1, 2022 and December 31, 2023

You may qualify if:

  • Adult patients who underwent colposcopy with directed biopsies at La Pitié-Salpêtrière between September 1, 2022 and December 31, 2023
  • Known clinical context (why the patient underwent colposcopy)
  • Histological results of cervical biopsies (+/- conization or even hysterectomy) known
  • Images available (photographs of the cervix without preparation, after application of acetic acid and after application of lugol)
  • Informed of the study and not opposing the use of their data

You may not qualify if:

  • Patients who do not speak French

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Uterine Cervical Neoplasms

Interventions

Data Collection

Condition Hierarchy (Ancestors)

Uterine NeoplasmsGenital Neoplasms, FemaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsUterine Cervical DiseasesUterine DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital Diseases

Intervention Hierarchy (Ancestors)

Epidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Central Study Contacts

Geoffroy CANLORBE, MD, PhD

CONTACT

Pierre MATHON

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Target Duration
2 Months
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 4, 2024

First Posted

January 17, 2024

Study Start

March 1, 2024

Primary Completion

October 31, 2024

Study Completion

October 31, 2024

Last Updated

February 1, 2024

Record last verified: 2024-01

Data Sharing

IPD Sharing
Will share

The procedures carried out with the French data privacy authority (CNIL, Commission nationale de l'informatique et des libertés) do not provide for the transmission of the database, nor do the information and consent documents signed by the patients. Consultation by the editorial board or interested researchers of individual participant data that underlie the results reported in the article after deidentification may nevertheless be considered, subject to prior determination of the terms and conditions of such consultation and in respect for compliance with the applicable regulations.

Shared Documents
STUDY PROTOCOL, ICF
Time Frame
Beginning 3 months and ending 3 years following article publication. Requests out of these time frame can also be submitted to the sponsor
Access Criteria
Researchers who provide a methodologically sound proposal.