Role of the Intrapartum Grobman Nomogram in the Indication of Attempted Vaginal Delivery After Cesarean Section

NCT06202768 | Not Yet Recruiting

• 1 other identifier: 2023PI211
• Study Type: observational
• Target: 800
• Locations: 1 country
• Sites: 1

Brief Summary

The rate of pregnant patients with a history of cesarean section is increasing. Caesarean section is a surgery which is not without risk and in particular concerning the risk of uterine rupture and malplacentation during a new pregnancy. Considering the outcome of a new birth following a cesarean section is not easy. There is no reliable score to predict the success rate of vaginal delivery with a history of scarred uterus. The aim of our study would be to validate the intrapartum Grobman nomogram within the population of the Nancy University Hospital and thus to target the population for whom vaginal delivery could be offered.

Conditions

Vaginal Delivery

Outcome Measures

Primary Outcomes (1)

• Modified Grobman score

  calculate Grobman score according to different criteria. If the score is high, the probability of vaginal delivery is high. This a score which calculates probability of vaginal delivery thanks to 11 parameters (maternal âge, BMI, previous vaginal delivery before and after ceasection, recurring indication, gestational age, hypertensive disease of pregnancy, effacement, dilatation, foetal station, labor induction)

  per-partum, 9 months

Study Arms (1)

Main population

History of cesarean section Vertex singleton gestation At term (at least 37 weeks of gestation)

Other: data collection

Interventions

data collection OTHER

data collection : age, gestational age, BMI, history of vaginal delivery after cesarean section, indication for cesarean section, preeclampsia for this pregnancy, the cervix dilatation, position in the pelvis, cervix consistency

Main population

Eligibility Criteria

• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Population of women who gave birth at the Nancy maternity ward and met the inclusion criteria, from January 2014 to January 2021.

You may qualify if:

• Vertex singleton pregnancy
• Full-term delivery (beyond 37 weeks)
• A history of cesarean section (segmental transverse scar)

You may not qualify if:

• Fetal death in utero

Sponsors & Collaborators

• Central Hospital, Nancy, France: lead

Study Sites (1)

Maternity

Nancy, France

Location

MeSH Terms

Interventions

Data Collection

Intervention Hierarchy (Ancestors)

Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Charlotte COTTEZ

  Hospital, Nancy, France

  STUDY DIRECTOR

Central Study Contacts

Charlotte COTTEZ

CONTACT

0689677319; c.cottez@chru-nancy.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: post-resident

Study Record Dates

• First Submitted: January 1, 2024
• First Posted: January 12, 2024
• Study Start: May 1, 2024
• Primary Completion: May 1, 2024
• Study Completion: June 1, 2024
• Last Updated: April 17, 2024

Record last verified: 2024-04

Locations

FR (1)