The Value of TOI in Evaluating Renal Function Damage in Hypertensive Emergency Patients

NCT06201572 | Unknown

• 1 other identifier: AH-2023-001
• Study Type: observational
• Target: 300
• Locations: 0 countries
• Sites: N/A

Brief Summary

TOI was used to measure heart rate, respiration, blood pressure, heart rate variability and psychological stress. At the same time, the patient's urine protein, creatinine, urea nitrogen and other indicators were detected. According to different renal function, they were divided into observation group and control group, and 100 general inpatients with renal insufficiency were selected as positive control group. The relationship between TOI composite index and renal function in hypertensive emergency patients was compared.

Conditions

Hypertensive Emergency

Outcome Measures

Primary Outcomes (3)

• blood pressure

  Both systolic and diastolic Blood Pressure levels of enrolled patients

  2023-12-01 to 2024-12-31

• creatinine

  creatinine levels of enrolled patients

  2023-12-01 to 2024-12-31

• urea nitrogen

  urea nitrogen levels of enrolled patients

  2023-12-01 to 2024-12-31

Study Arms (3)

Observation group

Other: The relationship between TOI composite index and renal function in hypertensive emergency patients was compared

Control group

Positive control group

Interventions

The relationship between TOI composite index and renal function in hypertensive emergency patients was compared OTHER

The relationship between TOI composite index and renal function in hypertensive emergency patients was compared. The data management platform provides intelligent management of patients' out-of-hospital follow-up, and the dynamic physiological indicators and psychological assessment data of patients are mastered through the hospital port, so as to provide telemedicine guidance for patients, so as to improve the prognosis of hypertensive emergency patients.

Observation group

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients hospitalized for acute hypertension from January 2022 to December 2024 with onset time \<48 hours and blood pressure measured by standard sphygmomanometer: Systolic blood pressure (SBP)\>180mmHg and/or diastolic blood pressure (DBP)\>120mmHg, age \>18 years old, gender, stable vital signs, good compliance, complete and reliable medical records.

You may qualify if:

• Systolic blood pressure (SBP)\>180mmHg
• Diastolic blood pressure (DBP)\>120mmHg

You may not qualify if:

• Severe head and facial skin injury
• Cerebral hemorrhage or severe shock after admission
• Patients who insist on refusing to participate in this clinical tria
• Patients who could not participate in the study for other reasons.

Sponsors & Collaborators

• The Affiliated Hospital of Hangzhou Normal University: lead

MeSH Terms

Conditions

Hypertensive Crisis

Condition Hierarchy (Ancestors)

Hypertension; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 2, 2024
• First Posted: January 11, 2024
• Study Start: February 1, 2024
• Primary Completion: December 31, 2024
• Study Completion: December 31, 2024
• Last Updated: January 22, 2024

Record last verified: 2023-11