Anterior Cutaneus Nerve and Distal Adductor Canal Block With USG for Total Knee Replacement Analgesia

NCT06201195 | Completed

• 1 other identifier: AEŞH-EK1-2023-556
• Study Type: interventional
• Target: 58
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective clinical study was approved by the institutional ethics committee on September 27, 2023, and patient enrollment started in October 2023. the study aimed to evaluate the contribution of anterior femoral cutaneus nerve block to postoperative analgesia in total knee artroplasty. The goal of this clinical trial is to compare analhesia effects of adductor canal blockade versus distal adductur canal blockade added anterior cutaneus nerve block in total knee arthroplasty. The main questions it aims to answer are:

• question 1: does distal adductor canal blockade + anterior cutaneus nerve blokade superior analgesia then adductor canal block for undergoing TKP?
• question 2: does distal adductor canal blockade + anterior cutaneus nerve blokade decrease drain place pain on anterolateral face of knee?

Conditions

Pain Measurement; Knee Replacement Arthroplasty; Nerve Block

Keywords

anterior femoral cutaneus nerve block; distal adductor canal block; total knee arthroplasthy

Outcome Measures

Primary Outcomes (2)

• VAS (visuel analouge scale)

  for postoperative pain evaluation after TKA surgery. The visual analogue scale (VAS) uses a 10 cm line with endpoint descriptors such as 'no pain' marked at the left end of the line and 'worst pain imaginable' marked at the right end.

  postblock 3 hour,10 hour, 24 hour

• drain place pain

  do you have any pain on drain place? yes or no

  postblock 3 hour,10 hour, 24 hour

Secondary Outcomes (2)

• VAS movement

  postblock 3 hour,10 hour, 24 hour

• motor strenght

  postblock 3 hour,10 hour, 24 hour

Study Arms (2)

Adductor canal block

ACTIVE COMPARATOR

Usg guidance adductor canal block with %0.25 Bupivacaine 20 ml

Procedure: Adductor canal blockade

Distal adductor canal block with anterior cutaneus nerve block

ACTIVE COMPARATOR

Usg guidance distal adductor canal block (%0.25 Bupivacaine 20 ml) with anterior cutaneus nerve block (%0.25 Bupivacaine 10 ml)

Procedure: Distal adductor canala blockade and anterior cutaneus nerve blockade

Interventions

Adductor canal blockade PROCEDURE

VAS, VAS move, incision place pain for up and down to patella, drain place pain, motor strenght for femoral nerve and siyatic nerve muscles, side effects, first analgesic requirement time, opioid requirement, other analgesics

Also known as: first control

Adductor canal block

Distal adductor canala blockade and anterior cutaneus nerve blockade PROCEDURE

VAS, VAS move, incision place pain for up and down to patella, drain place pain, motor strenght for femoral nerve and siyatic nerve muscles, side effects, first analgesic requirement time, opioid requirement, other analgesics

Also known as: study group

Distal adductor canal block with anterior cutaneus nerve block

Eligibility Criteria

• Age: 40 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Total knee artroplasty
• Spinal anesthesia
• ASA 1-3

You may not qualify if:

• Bupivacaine allergy
• Coagulopathy
• Infection on injection site

Sponsors & Collaborators

• Diskapi Teaching and Research Hospital: lead

Study Sites (1)

Ankara Etlik City Hospital

Ankara, Turkey (Türkiye)

Location

Related Publications (1)

• Bjorn S, Nielsen TD, Moriggl B, Hoermann R, Bendtsen TF. Anesthesia of the anterior femoral cutaneous nerves for total knee arthroplasty incision: randomized volunteer trial. Reg Anesth Pain Med. 2019 Dec 10:rapm-2019-100904. doi: 10.1136/rapm-2019-100904. Online ahead of print.

  PMID: 31826920 BACKGROUND

Study Officials

• Derya Ozkan

  Study Principal Investigator Ankara Etlik City Hospital

  STUDY DIRECTOR

• Müge Çakırca, doctor

  Study Principal Investigator Ankara Etlik City Hospital

  PRINCIPAL INVESTIGATOR

• Funda Atar, doctor

  Study Principal Investigator Ankara Etlik City Hospital

  STUDY CHAIR

• Serhan ünlü, doctor

  Study Principal Investigator Ankara Etlik City Hospital

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: professor

Study Record Dates

• First Submitted: October 25, 2023
• First Posted: January 11, 2024
• Study Start: October 1, 2023
• Primary Completion: March 31, 2024
• Study Completion: June 30, 2024
• Last Updated: November 19, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)