Indoor Air Quality Monitoring and Impact on Children's Health

NCT06197477 | Unknown

• 1 other identifier: Hasselt University
• Study Type: interventional
• Target: 900
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims at understanding the relation between indoor air quality in schools, including both chemical and microbiological determinants, and cognition in children by gathering data across different parts of Europe

Conditions

Cognition

Keywords

indoor air pollution; indoor air quality; cognition in children

Outcome Measures

Primary Outcomes (4)

• Change in Correct Detection of continuous Performance Test

  Change in the number of times the child responded correctly to the target alphanumeric stimulus. Higher rates of correct detections indicate better attentional capacity.

  at the end of the intervention and at the end of the sham intervention

• Change in the number of correct substitutions of Symbol Digit Modalities Test

  Change in the the number of correct substitutions the child performed. Higher number of correct substitutions indicate better information processing ability.

  at the end of the intervention and at the end of the sham intervention

• Change in the Memory Span Task score

  Change in the number of longest list of items that a child can repeat back in correct order. Longer list of recalled items indicate better short term memory

  at the end of the intervention and at the end of the sham intervention

• Change in the Signal Detection Test score

  Change in the number of correct detection of signals. Higher rates of correct detection indicate better perception ability

  at the end of the intervention and at the end of the sham intervention

Study Arms (2)

Air purification

EXPERIMENTAL

The intervention will consist of air purification placed in the classrooms.

Device: OurAir SQ 1750 - Mobile Air Purification System for indoor

Control

SHAM COMPARATOR

Filtration will be turned off in the air purifier placed in the classrooms in the control part of the study.

Device: Sham intervention

Interventions

OurAir SQ 1750 - Mobile Air Purification System for indoor DEVICE

Filtration device will be placed in classrooms. Computational Fluid Dynamics simulations will be used to find optimal position and operation mode for air purification systems in classrooms.

Air purification

Sham intervention DEVICE

Filtration will be turned off in the control part of the study and then will be turned on during the intervention.

Control

Eligibility Criteria

• Age: 9 Years - 12 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Boys and girls
• Attending school in the 4th -6th grade in elementary schools included in the study
• Signed informed consent form by legal representative

You may not qualify if:

• Insufficient knowledge of local language (ie. Dutch, Greek, Danish) by child or parents

Sponsors & Collaborators

• Hasselt University: lead

Study Sites (1)

Hasselt University

Diepenbeek, 3590, Belgium

RECRUITING

Study Officials

• Tim Nawrot, PhD

  Hasselt University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Rossella Alfano, PhD

CONTACT

+3281739400; rossella.alfano@uhasselt.be

Nawrot

CONTACT

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 28, 2023
• First Posted: January 9, 2024
• Study Start: November 20, 2023
• Primary Completion: December 1, 2025
• Study Completion: December 1, 2025
• Last Updated: January 9, 2024

Record last verified: 2024-01

Data Sharing

• IPD Sharing: Will not share

Locations

BE (1)