Development of Delirium in Patients Undergoing Open-Heart Surgery

NCT06195592 | Unknown DMC

• 1 other identifier: 2023-16/16
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Malnutrition is a prevalent issue among patients undergoing cardiac surgery. This can lead to delirium risk factors, including postoperative functional and cognitive impairment. Assessing the patient's nutritional status before open-heart surgery may decrease the incidence of delirium and the psychological and physiological problems associated with it. The objective of this study was to examine the relationship between nutritional status and the incidence of postoperative delirium in patients who have undergone open-heart surgery.

Conditions

Open-Heart Surgery

Keywords

delirium; malnutrition; open-heart surgery

Outcome Measures

Primary Outcomes (1)

• Recognising Delirium

  Recognising delirium in malnourished patients prior to open heart surgery

  6 months

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

To be eligible for the study, the patient must be at least 18 years old and have undergone open-heart surgery. They should not have any mental or sensory impairments, psychiatric diagnoses, or be taking medication for this purpose. Additionally, they should not be in a coma, with a RASS score between -3 and +4 and a GCS score of 10 or higher.

You may qualify if:

• Over 18 years old
• Having undergone open heart surgery
• No mental deficiency and visual and hearing impairment
• No psychiatric diagnosis and no medication for this purpose
• Participants' acceptance to participate in the research
• The patient is not in coma (RASS score between -3 and +4, GCS score of 10 and above)

You may not qualify if:

• Open heart surgery under emergency conditions
• Diagnosed with delirium, dementia, psychiatric illness before surgery
• Alcohol and drug addiction
• Dying in the intensive care unit within 24 hours

Sponsors & Collaborators

• Kubra Gunes: lead

Study Sites (1)

Bursa Uludag University

Bursa, Turkey (Türkiye)

Location

Related Publications (3)

• European Delirium Association; American Delirium Society. The DSM-5 criteria, level of arousal and delirium diagnosis: inclusiveness is safer. BMC Med. 2014 Oct 8;12:141. doi: 10.1186/s12916-014-0141-2.

  PMID: 25300023 RESULT

• Wilson JE, Mart MF, Cunningham C, Shehabi Y, Girard TD, MacLullich AMJ, Slooter AJC, Ely EW. Delirium. Nat Rev Dis Primers. 2020 Nov 12;6(1):90. doi: 10.1038/s41572-020-00223-4.

  PMID: 33184265 RESULT

• Velayati A, Vahdat Shariatpanahi M, Shahbazi E, Vahdat Shariatpanahi Z. Association between preoperative nutritional status and postoperative delirium in individuals with coronary artery bypass graft surgery: A prospective cohort study. Nutrition. 2019 Oct;66:227-232. doi: 10.1016/j.nut.2019.06.006. Epub 2019 Jun 14.

  PMID: 31357095 RESULT

MeSH Terms

Conditions

Delirium; Malnutrition

Condition Hierarchy (Ancestors)

Confusion; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurocognitive Disorders; Mental Disorders; Nutrition Disorders; Nutritional and Metabolic Diseases

Study Officials

• Nursel Vatansever

  Uludag University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: RN, MSc

Study Record Dates

• First Submitted: December 22, 2023
• First Posted: January 8, 2024
• Study Start: September 15, 2023
• Primary Completion: October 31, 2024
• Study Completion: November 30, 2024
• Last Updated: January 8, 2024

Record last verified: 2023-12

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)