Constructing a Model of Pupillary Parameters in Predicting Delirium Among Critically Ill Patients in the Intensive Unit

NCT06187792 | Unknown

• 1 other identifier: 202306099DINA
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Delirium is commonly observed in critically ill patients in intensive care units (ICUs), imposing significant burdens on both patients and the healthcare system. Existing assessment tools have certain limitations. Studies have indicated a correlation between pupil parameters and neurological disorders including delirium. Automated Infrared Pupillometry, widely used in neurological disorders, is employed in this study to assess its accuracy and predictive power in evaluating delirium among critically ill patients. The aim is to investigate the accuracy and predictive capability of these parameters in assessing delirium, while identifying the optimal cut-off points. The research findings will contribute to enhancing early detection and prevention of delirium in ICU settings.

Conditions

ICU Delirium

Keywords

Delirium; Predicting delirium; Automated Infrared Pupillometry (AIP); Pupil Parameters; Intensive Care Delirium Screening Checklist (ICDSC)

Outcome Measures

Primary Outcomes (1)

• Constructing a model based on pupillary parameters and delirium:

  By analyzing the relationship between pupillary parameters and delirium, identifying the optimal cut-off point, and constructing a formula.

  2023/09/1-2025/08/30

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients admitted to the intensive care unit from internal and surgical departments.

You may qualify if:

• Patients admitted to the intensive care unit from internal and surgical departments.
• Ages 18 and above.

You may not qualify if:

• Acute brain injury (hemorrhagic, ischemic stroke).
• Other brain-related diseases (brain tumor, brain infection, oculomotor nerve paralysis, etc.).
• Ophthalmic diseases that prevent monitoring of pupil measurements.
• Patients with pre-hospital cardiac arrest or in-hospital cardiac arrest.
• Estimated stay in the intensive care unit not exceeding 72 hours.
• Refusal to participate in this study.

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

Ming-Chen Chiang

Taipei, 220, Taiwan

RECRUITING

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MeSH Terms

Conditions

Delirium

Condition Hierarchy (Ancestors)

Confusion; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurocognitive Disorders; Mental Disorders

Central Study Contacts

Ming-Chen Chiang

CONTACT

(886) 02-23123456; jane.c0203@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 17, 2023
• First Posted: January 3, 2024
• Study Start: October 4, 2023
• Primary Completion: September 1, 2025
• Study Completion: September 1, 2025
• Last Updated: January 3, 2024

Record last verified: 2023-10

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)